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NCT04971148 · ClinicalTrials.gov registry record · NA
Correlation of Peak Tidal Inspiratory Flow Measured Before and After Extubation in Adult Patients With Hypoxemia
A NA study, sponsored by Rush University Medical Center.
- Terminated
- Registry status
- NA
- Development phase
- 5
- Enrollment target
NCT04971148: Clinical Trial NA study, sponsored by Rush University Medical Center.
NCT04971148 is a NA study that was terminated before completion, run by Rush University Medical Center. The registered enrollment target is 5 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (100% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04971148, a NA study, was terminated before completion, sponsored by Rush University Medical Center.
- TERMINATED
- Registry status
- NA
- Development phase
- 5 participants
- Enrollment target
Study Summary
In this study, patients who are ready for extubation and indicated for high-flow nasal cannula therapy after extubation will be enrolled, the investigators would measure the patient peak tidal inspiratory flow (PTIF) pre and post extubation to explore the correlation between the two PTIFs. Moreover, different HFNC flows would be applied, to explore the patient response in terms of oxygenation and lung aeration to different flow ratios that matched and are above post-extubation PTIF.
Primary Outcome
Twenty mins after each flow setting, pulse oximetry divided by fraction of inspired oxygen will be used to assess patient's oxygenation response to different flow
Interventions
- OTHER HFNC flow set at patient peak tidal inspiratory flow
- OTHER HFNC flow set at 1.33 times of patient peak tidal inspiratory flow
- OTHER HFNC flow set at 1.67 times of patient peak tidal inspiratory flow
- OTHER HFNC flow set at 2 times of patient peak tidal inspiratory flow
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 5 participants |
| Start Date | 2022-04-07 |
| Est. Completion | 2023-08-08 |
| Phase | NA |
Why NCT04971148 stopped before completion
NCT04971148 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 5 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (100% lower).
The record links to 0 conditions, and to 4 interventions - of which HFNC flow set at patient peak tidal inspiratory flow is the first listed.
NCT04971148 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04971148 about?
NCT04971148 is a clinical study titled "Correlation of Peak Tidal Inspiratory Flow Measured Before and After Extubation in Adult Patients With Hypoxemia". In this study, patients who are ready for extubation and indicated for high-flow nasal cannula therapy after extubation will be enrolled, the investigators would measure the patient peak tidal inspiratory flow (PTIF) pre and post extubation to explore the correlation between the two PTIFs. Moreover,...
What is the current status of trial NCT04971148?
This trial is currently terminated. It is a NA study. The enrollment target is 5 participants. The study started on 2022-04-07. Estimated completion is 2023-08-08.
What interventions are being tested in trial NCT04971148?
The interventions under investigation include: HFNC flow set at patient peak tidal inspiratory flow (OTHER), HFNC flow set at 1.33 times of patient peak tidal inspiratory flow (OTHER), HFNC flow set at 1.67 times of patient peak tidal inspiratory flow (OTHER), HFNC flow set at 2 times of patient peak tidal inspiratory flow (OTHER).
Who is sponsoring clinical trial NCT04971148?
This trial is sponsored by Rush University Medical Center, which has 320 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04971148's enrollment target sits among peer trials
5 1988th of 2000 higher than 5 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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