Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT04967989 · ClinicalTrials.gov registry record · Phase 3
Clarifying the Optimal Application of SLT Therapy Trial
A Phase 3 study of Glaucoma and Ocular Hypertension, sponsored by University of Pittsburgh.
- Recruiting
- Registry status
- Phase 3
- Development phase
- 790
- Enrollment target
- 20
- Study locations
NCT04967989: Recruiting Phase 3 study of Glaucoma and Ocular Hypertension, sponsored by University of Pittsburgh.
NCT04967989 is a Phase 3 study of Glaucoma and Ocular Hypertension that is actively recruiting participants, run by University of Pittsburgh. The registered enrollment target is 790 participants, roughly in line with the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target. The trial reports 20 study locations across 11 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04967989, a Phase 3 study of Glaucoma and Ocular Hypertension, is actively recruiting participants, sponsored by University of Pittsburgh.
- RECRUITING
- Registry status
- Phase 3
- Development phase
- 790 participants
- Enrollment target
- 20
- Study locations
Study Summary
The goal of this study is to understand if SLT performed at low energy is as effective as SLT performed at standard energy, and also to see if repeating SLT at low energy once a year will prevent or delay the need for daily eye drop medications better than waiting for SLT to wear off before repeating it.
Primary Outcome
Survival of first SLT through Month 12
Conditions Studied
Interventions
- PROCEDURE Low Energy SLT
- PROCEDURE Standard Energy SLT
Study Locations (20)
California
- Harvard Eye Associates - Laguna Hills
- Doheny Eye Center UCLA - Pasadena
- University of California, Davis - Sacramento
- University of California, San Francisco - San Francisco
Illinois
- Northwestern Medical Group - Chicago
- Chicago Arbor Eye Institute - Orland Park
- Illinois Eye Center - Peoria
Massachusetts
- Massachusetts Eye and Ear - Boston
- Ophthalmic Consultants of Boston - Boston
- Mark Latina, LLC - Reading
Michigan
- University of Michigan Kellogg Eye Center - Ann Arbor
- Kresge Eye Institute Wayne State University - Detroit
Ohio
- University Hospitals Eye Institute - Cleveland
- Cleveland Clinic Cole Eye Institute - Cleveland
Colorado
- Mile High Eye Institute - Sheridan
Florida
- Clear Vue Laser Eye Center - Lakeworth
Maryland
- Wilmer Eye Institute Johns Hopkins - Baltimore
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 790 participants |
| Start Date | 2021-09-07 |
| Est. Completion | 2027-08-31 |
| Phase | Phase 3 |
What NCT04967989 shows while recruiting
NCT04967989 is an interventional study that assigns participants to a tested intervention. The registered 790 participants enrollment target is mid-sized for trials with a published cap, roughly in line with the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target.
The record links to 1 condition, with Glaucoma and Ocular Hypertension appearing as the primary indexed condition, and to 2 interventions - of which Low Energy SLT is the first listed.
NCT04967989 names 20 study sites across 11 states, led by California, Illinois, Massachusetts.
Frequently Asked Questions
What is clinical trial NCT04967989 about?
NCT04967989 is a clinical study titled "Clarifying the Optimal Application of SLT Therapy Trial". The goal of this study is to understand if SLT performed at low energy is as effective as SLT performed at standard energy, and also to see if repeating SLT at low energy once a year will prevent or delay the need for daily eye drop medications better than waiting for SLT to wear off before repeatin...
What is the current status of trial NCT04967989?
This trial is currently recruiting. It is a Phase 3 study. The enrollment target is 790 participants. The study started on 2021-09-07. Estimated completion is 2027-08-31.
What conditions does trial NCT04967989 study?
This clinical trial studies the following conditions: Glaucoma and Ocular Hypertension.
What interventions are being tested in trial NCT04967989?
The interventions under investigation include: Low Energy SLT (PROCEDURE), Standard Energy SLT (PROCEDURE).
Who is sponsoring clinical trial NCT04967989?
This trial is sponsored by University of Pittsburgh, which has 1,238 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04967989 being conducted?
This trial has 20 study locations across California, Colorado, Florida, Illinois, Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Glaucoma and Ocular Hypertension
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04967989's enrollment target sits among peer trials
790 429th of 2000 higher than 1,571 of 2,000 other Phase 3 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT06162611 · 790 participants · Phase 4
Etonogestrel (ENG) Implant Insertion for Emergency Contraception With Oral Levonorgestrel (LNG) vs Placebo
- NCT03424005 · 792 participants · Phase 1
A Study Evaluating the Efficacy and Safety of Multiple Treatment Combinations in Patients With Metastatic or Locally Advanced Breast Cancer
- NCT05866081 · 792 participants · NA
Stent Omission After Ureteroscopy and Lithotripsy in the Michigan Urological Surgery Improvement Collaborative
- NCT06722352 · 792 participants · NA
Palliative Care Education in Assisted Living for Dementia Care Providers (PCEAL-DCP)
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI