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NCT04967599 · ClinicalTrials.gov registry record · NA
Alcohol Metabolism and Disease Risk in Asians
A NA study, sponsored by University of Southern California.
- Completed
- Registry status
- NA
- Development phase
- 360
- Enrollment target
NCT04967599: Completed NA study, sponsored by University of Southern California.
NCT04967599 is a NA study that has completed, run by University of Southern California. The registered enrollment target is 360 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (74% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04967599, a NA study, has completed, sponsored by University of Southern California.
- COMPLETED
- Registry status
- NA
- Development phase
- 360 participants
- Enrollment target
Study Summary
The primary pathway of alcohol metabolism involves two main enzymes, alcohol and aldehyde dehydrogenase. Several genes that encode these enzymes have variants that alter the rate of alcohol metabolism and increase levels of acetaldehyde. The variant ALDH2\*2 allele is associated with the flushing response (i.e., Asian glow) and is found almost exclusively in individuals of east Asian descent. Although having variant ALDH2 alleles is protective against heavy drinking and alcohol use disorders, for those who do drink, these variants also are associated with elevations in risk for several health problems. The premise of this study is that we can affect early drinking behavior through personalized communication about these health-related risks.
Primary Outcome
Drinking quantity (i.e. total number of alcoholic drinks) consumed on heaviest drinking day
Interventions
- BEHAVIORAL Phenotype Feedback Intervention
- BEHAVIORAL Genotype Feedback Intervention
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 360 participants |
| Start Date | 2021-08-18 |
| Est. Completion | 2023-01-18 |
| Phase | NA |
What the finished NCT04967599 record still lists
NCT04967599 is an interventional study that assigns participants to a tested intervention. The registered 360 participants enrollment target is mid-sized for trials with a published cap, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (74% lower).
The record links to 0 conditions, and to 2 interventions - of which Phenotype Feedback Intervention is the first listed.
NCT04967599 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04967599 about?
NCT04967599 is a clinical study titled "Alcohol Metabolism and Disease Risk in Asians". The primary pathway of alcohol metabolism involves two main enzymes, alcohol and aldehyde dehydrogenase. Several genes that encode these enzymes have variants that alter the rate of alcohol metabolism and increase levels of acetaldehyde. The variant ALDH2\*2 allele is associated with the flushing re...
What is the current status of trial NCT04967599?
This trial is currently completed. It is a NA study. The enrollment target is 360 participants. The study started on 2021-08-18. Estimated completion is 2023-01-18.
What interventions are being tested in trial NCT04967599?
The interventions under investigation include: Phenotype Feedback Intervention (BEHAVIORAL), Genotype Feedback Intervention (BEHAVIORAL).
Who is sponsoring clinical trial NCT04967599?
This trial is sponsored by University of Southern California, which has 617 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04967599's enrollment target sits among peer trials
360 284th of 2000 higher than 1,713 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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