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NCT04959266 · ClinicalTrials.gov registry record · Phase 1

A Study to Assess the Effects of Itraconazole, Rifampicin, and Omeprazole on Pharmacokinetics of Adavosertib

A Phase 1 study, sponsored by AstraZeneca.

Terminated
Registry status
Phase 1
Development phase
5
Enrollment target

NCT04959266 is a Phase 1 study that was terminated before completion, run by AstraZeneca. The registered enrollment target is 5 participants.

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The verdict

NCT04959266, a Phase 1 study, was terminated before completion, sponsored by AstraZeneca.

TERMINATED
Registry status
Phase 1
Development phase
5 participants
Enrollment target

Study Summary

This is a Phase 1, open-label, non-randomised, 3-arm (A, B, and C), drug-drug interaction study in patients with advanced solid tumours.

Interventions

  • DRUG Itraconazole
  • DRUG Omeprazole
  • DRUG Adavosertib
  • DRUG Rifampicin

Trial Details

FieldValue
Enrollment Target 5 participants
Start Date 2021-06-28
Est. Completion 2022-06-01
Phase Phase 1

Sponsor

AstraZeneca

1,285 total trials

What the Registry Record Tells You About NCT04959266

The ClinicalTrials.gov registry entry for NCT04959266 describes a study currently listed as terminated, categorized as Phase 1. The registered enrollment target is 5 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is AstraZeneca, which has 1,285 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 4 interventions - of which Itraconazole is the first listed.

NCT04959266 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT04959266 about?

NCT04959266 is a clinical study titled "A Study to Assess the Effects of Itraconazole, Rifampicin, and Omeprazole on Pharmacokinetics of Adavosertib". This is a Phase 1, open-label, non-randomised, 3-arm (A, B, and C), drug-drug interaction study in patients with advanced solid tumours.

What is the current status of trial NCT04959266?

This trial is currently terminated. It is a Phase 1 study. The enrollment target is 5 participants. The study started on 2021-06-28. Estimated completion is 2022-06-01.

What interventions are being tested in trial NCT04959266?

The interventions under investigation include: Itraconazole (DRUG), Omeprazole (DRUG), Adavosertib (DRUG), Rifampicin (DRUG).

Who is sponsoring clinical trial NCT04959266?

This trial is sponsored by AstraZeneca, which has 1,285 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.