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NCT04956120 · ClinicalTrials.gov registry record · NA
Effect of Citrate Dialysate on Vascular Calcification
A NA study, sponsored by Emory University.
- Completed
- Registry status
- NA
- Development phase
- 54
- Enrollment target
NCT04956120: Completed NA study, sponsored by Emory University.
NCT04956120 is a NA study that has completed, run by Emory University. The registered enrollment target is 54 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (96% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04956120, a NA study, has completed, sponsored by Emory University.
- COMPLETED
- Registry status
- NA
- Development phase
- 54 participants
- Enrollment target
Study Summary
The goal of this study is to determine whether hemodialysis with citrate slows the progression of vascular calcification. Participants will be dialyzed with one of two standard dialysis solutions, one with and one without citrate, for 12 months and then switched to the other solution for 12 months. Vascular calcification will be measured on mammograms that will be performed at 6-month intervals and additional blood samples will be obtained at 6-month intervals.
Primary Outcome
Rate of progression of breast arterial calcification (BAC) is calculated by linear regression of 3 mammograms over one year in each treatment arm (Months 0, 6 and 12 versus Months 12, 18 and 24). Progression of calcification is quantified as the length of calcified artery segments per year, measured in millimeters. Slower progression of vascular calcification, indicated by lower values, is a desirable outcome.
Interventions
- DEVICE Citrate Dialysate
- DEVICE Standard Dialysate
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 54 participants |
| Start Date | 2021-05-27 |
| Est. Completion | 2025-03-18 |
| Phase | NA |
What the finished NCT04956120 record still lists
NCT04956120 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 54 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (96% lower).
The record links to 0 conditions, and to 2 interventions - of which Citrate Dialysate is the first listed.
NCT04956120 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04956120 about?
NCT04956120 is a clinical study titled "Effect of Citrate Dialysate on Vascular Calcification". The goal of this study is to determine whether hemodialysis with citrate slows the progression of vascular calcification. Participants will be dialyzed with one of two standard dialysis solutions, one with and one without citrate, for 12 months and then switched to the other solution for 12 months. ...
What is the current status of trial NCT04956120?
This trial is currently completed. It is a NA study. The enrollment target is 54 participants. The study started on 2021-05-27. Estimated completion is 2025-03-18.
What interventions are being tested in trial NCT04956120?
The interventions under investigation include: Citrate Dialysate (DEVICE), Standard Dialysate (DEVICE).
Who is sponsoring clinical trial NCT04956120?
This trial is sponsored by Emory University, which has 1,208 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04956120's enrollment target sits among peer trials
54 1268th of 2000 higher than 730 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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