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NCT04952597 · ClinicalTrials.gov registry record · Phase 2

Study of Ociperlimab Plus Tislelizumab Plus Chemoradiotherapy in Participants With Untreated Limited-Stage Small Cell Lung Cancer

A Phase 2 study, sponsored by BeiGene.

Completed
Registry status
Phase 2
Development phase
126
Enrollment target

NCT04952597: Completed Phase 2 study, sponsored by BeiGene.

NCT04952597 is a Phase 2 study that has completed, run by BeiGene. The registered enrollment target is 126 participants, roughly in line with the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT04952597, a Phase 2 study, has completed, sponsored by BeiGene.

COMPLETED
Registry status
Phase 2
Development phase
126 participants
Enrollment target

Study Summary

This phase 2 trial examined whether the preliminary efficacy and safety of ociperlimab, tislelizumab, and cCRT when used in combination is expected to advance treatment options in the serious unmet medical need population of Limited-Stage Small Cell Lung Cancer (LS-SCLC) participants .

Primary Outcome

Defined as the time from the date of randomization to the date of the first documented disease progression as determined by the investigator per RECIST v1.1 or death from any cause (whichever occurs first)

Interventions

  • DRUG Tislelizumab
  • DRUG Ociperlimab
  • DRUG Concurrent Chemoradiotherapy

Trial Details

FieldValue
Enrollment Target 126 participants
Start Date 2021-07-15
Est. Completion 2023-07-26
Phase Phase 2
BeiGene

65 total trials

What the finished NCT04952597 record still lists

NCT04952597 is an interventional study that assigns participants to a tested intervention. The registered 126 participants enrollment target is mid-sized for trials with a published cap, roughly in line with the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target.

The record links to 0 conditions, and to 3 interventions - of which Tislelizumab is the first listed.

NCT04952597 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT04952597 about?

NCT04952597 is a clinical study titled "Study of Ociperlimab Plus Tislelizumab Plus Chemoradiotherapy in Participants With Untreated Limited-Stage Small Cell Lung Cancer". This phase 2 trial examined whether the preliminary efficacy and safety of ociperlimab, tislelizumab, and cCRT when used in combination is expected to advance treatment options in the serious unmet medical need population of Limited-Stage Small Cell Lung Cancer (LS-SCLC) participants .

What is the current status of trial NCT04952597?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 126 participants. The study started on 2021-07-15. Estimated completion is 2023-07-26.

What interventions are being tested in trial NCT04952597?

The interventions under investigation include: Tislelizumab (DRUG), Ociperlimab (DRUG), Concurrent Chemoradiotherapy (DRUG).

Who is sponsoring clinical trial NCT04952597?

This trial is sponsored by BeiGene, which has 65 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT04952597's enrollment target sits among peer trials

126 556th of 2000 higher than 1,443 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT04952597, the US trial registry maintained by the National Library of Medicine. NCT04952597 (mid enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.