Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT04946084 · ClinicalTrials.gov registry record · NA
Dynamic Change and Immune Response to Nasopharyngeal Carriage and Acute Otitis Media Pathogens
A NA study of Acute Otitis Media, sponsored by Rochester General Hospital.
- Active
- Registry status
- NA
- Development phase
- 320
- Enrollment target
- 1
- Study location
NCT04946084: Active NA study of Acute Otitis Media, sponsored by Rochester General Hospital.
NCT04946084 is a NA study of Acute Otitis Media that is active but no longer recruiting, run by Rochester General Hospital. The registered enrollment target is 320 participants, below the 367-participant average among 8 other Acute Otitis Media trials with a reported enrollment target (13% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04946084, a NA study of Acute Otitis Media, is active but no longer recruiting, sponsored by Rochester General Hospital.
- ACTIVE NOT RECRUITING
- Registry status
- NA
- Development phase
- 320 participants
- Enrollment target
- 1
- Study location
Study Summary
The investigators seek to conduct a prospective, longitudinal study to identify the dynamic changes in nasopharyngeal (NP) colonization patterns and acute otitis media (AOM) etiology involving antibiotic-resistant Streptococcus pneumoniae (Spn) and Haemophilus influenzae (Hflu).
Primary Outcome
Identify the presence of Streptococcus pneumoniae, Haemophilus influenzae and Moraxella catharralis in the nasopharynx of children using in vitro culture
Conditions Studied
Interventions
- OTHER Blood Draw
- PROCEDURE Tympanocentesis
- OTHER Nasal Phalangeal Swab and Wash
Study Locations (1)
New York
- Rochester General Hospital - Rochester
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 320 participants |
| Start Date | 2021-01-01 |
| Est. Completion | 2026-12-31 |
| Phase | NA |
What the registry record for NCT04946084 still lists
NCT04946084 is an interventional study that assigns participants to a tested intervention. The registered 320 participants enrollment target is mid-sized for trials with a published cap, below the 367-participant average among 8 other Acute Otitis Media trials with a reported enrollment target (13% lower).
The record links to 1 condition, with Acute Otitis Media appearing as the primary indexed condition, and to 3 interventions - of which Blood Draw is the first listed.
NCT04946084 reports a single indexed study location in New York.
Frequently Asked Questions
What is clinical trial NCT04946084 about?
NCT04946084 is a clinical study titled "Dynamic Change and Immune Response to Nasopharyngeal Carriage and Acute Otitis Media Pathogens". The investigators seek to conduct a prospective, longitudinal study to identify the dynamic changes in nasopharyngeal (NP) colonization patterns and acute otitis media (AOM) etiology involving antibiotic-resistant Streptococcus pneumoniae (Spn) and Haemophilus influenzae (Hflu).
What is the current status of trial NCT04946084?
This trial is currently active not recruiting. It is a NA study. The enrollment target is 320 participants. The study started on 2021-01-01. Estimated completion is 2026-12-31.
What conditions does trial NCT04946084 study?
This clinical trial studies the following conditions: Acute Otitis Media.
What interventions are being tested in trial NCT04946084?
The interventions under investigation include: Blood Draw (OTHER), Tympanocentesis (PROCEDURE), Nasal Phalangeal Swab and Wash (OTHER).
Who is sponsoring clinical trial NCT04946084?
This trial is sponsored by Rochester General Hospital, which has 6 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04946084 being conducted?
This trial has 1 study location across New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Acute Otitis Media
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04946084's enrollment target sits among peer trials
320 4th of 8 higher than 5 of 8 other Acute Otitis Media trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Acute Otitis Media trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
-
Interventions to De-implement Unnecessary Antibiotic Prescribing for Children With Ear Infections
RECRUITING · NA
-
RELAX: Reducing Length of Antibiotics for Children With Ear Infections
ACTIVE NOT RECRUITING · NA
-
Pediatric Emergency Department Smartphone Otoscope Study (PED-Oto)
COMPLETED · NA
-
Evaluation of Outcomes Following In-office Tympanostomy Using the Tula® System: a Prospective, Multi-center Registry
RECRUITING
-
Phase III Study Evaluating Topical Benzocaine for Treatment of Acute Otitis Media in Children
COMPLETED · Phase 3
-
Evaluation of the Tympanostomy Tube Delivery System
COMPLETED · Phase 2
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT02763683 · 320 participants
Investigations of Dementia in Parkinson Disease
- NCT03331198 · 320 participants · Phase 1
Study Evaluating Safety and Efficacy of JCAR017 in Subjects With Relapsed or Refractory Chronic Lymphocytic Leukemia (CLL) or Small Lymphocytic Lymphoma (SLL)
- NCT03458832 · 320 participants
Clinical Trial Readiness to Solve Barriers to Drug Development in FSHD
- NCT03551951 · 320 participants
Tumor Cell and DNA Detection in the Blood, Urine, and Bone Marrow
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI