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NCT04941430 · ClinicalTrials.gov registry record · NA

7T MRI Scan for the Early Detection of Melanoma Brain Metastases

A NA study, sponsored by University of Southern California.

Terminated
Registry status
NA
Development phase
2
Enrollment target

NCT04941430: Clinical Trial NA study, sponsored by University of Southern California.

NCT04941430 is a NA study that was terminated before completion, run by University of Southern California. The registered enrollment target is 2 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (100% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT04941430, a NA study, was terminated before completion, sponsored by University of Southern California.

TERMINATED
Registry status
NA
Development phase
2 participants
Enrollment target

Study Summary

This clinical trial studies the use of 7-Tesla (7T) magnetic resonance imaging (MRI) in detecting melanoma that has spread to the brain (melanoma brain metastases). The standard MRI brain imaging is done on 3T or similar MRI machine, but the 7T MRI machine has a larger magnet which has been shown to have superior resolution of the brain and of non-cancerous brain lesions. Diagnostic procedures such as 7T MRI may help find and diagnose melanoma brain metastases earlier than standard 3T MRI.

Primary Outcome

Any visualized brain metastases seen in this study on 3T will be evaluated using the criteria proposed by the Response Assessment in Neuro-Oncology Brain Metastases (RANO-BM). As there are no consensus criteria for 7T MRI published at this time, we will apply the same RANO-BM criteria to the study 7T MRI exams.Will count the discordant lesions between 3T and 7T, i.e. lesion identified in 7T but not 3T (L71L30) versus (vs.) lesion identified in 3T but not 7T(L70L31). McNemar's test will be used t

Interventions

  • DIAGNOSTIC_TEST Magnetic Resonance Imaging using 7 Tesla MRI

Trial Details

FieldValue
Enrollment Target 2 participants
Start Date 2021-06-25
Est. Completion 2025-01-10
Phase NA
University of Southern California

617 total trials

Why NCT04941430 stopped before completion

NCT04941430 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 2 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (100% lower).

The record links to 0 conditions, and to 1 intervention - of which Magnetic Resonance Imaging using 7 Tesla MRI is the first listed.

NCT04941430 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT04941430 about?

NCT04941430 is a clinical study titled "7T MRI Scan for the Early Detection of Melanoma Brain Metastases". This clinical trial studies the use of 7-Tesla (7T) magnetic resonance imaging (MRI) in detecting melanoma that has spread to the brain (melanoma brain metastases). The standard MRI brain imaging is done on 3T or similar MRI machine, but the 7T MRI machine has a larger magnet which has been shown to...

What is the current status of trial NCT04941430?

This trial is currently terminated. It is a NA study. The enrollment target is 2 participants. The study started on 2021-06-25. Estimated completion is 2025-01-10.

What interventions are being tested in trial NCT04941430?

The interventions under investigation include: Magnetic Resonance Imaging using 7 Tesla MRI (DIAGNOSTIC_TEST).

Who is sponsoring clinical trial NCT04941430?

This trial is sponsored by University of Southern California, which has 617 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT04941430's enrollment target sits among peer trials

2 1997th of 2000 the lowest of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT04941430, the US trial registry maintained by the National Library of Medicine. NCT04941430 (small enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.