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NCT04935697 · ClinicalTrials.gov registry record · NA

Non-invasive Vagal Neurostimulation (nVNS) for Traumatic Brain Injury (TBI)-Induced Acute Respiratory Distress

A NA study, sponsored by Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute).

Completed
Registry status
NA
Development phase
3
Enrollment target

NCT04935697 is a NA study that has completed, run by Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute). The registered enrollment target is 3 participants.

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The verdict

NCT04935697, a NA study, has completed, sponsored by Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute).

COMPLETED
Registry status
NA
Development phase
3 participants
Enrollment target

Study Summary

This is a prospective, randomized, two-arm, controlled 30-day investigational pilot trial using the gammaCore Sapphire S non-invasive vagus nerve stimulation (nVNS) device + standard of care (SOC) in newly-hospitalized patients with mild-to-moderate traumatic brain injury (TBI) to prevent the progression towards immunokine storms, systemic inflammatory response syndrome (SIRS), severe respiratory distress, and requirement for invasive mechanical ventilation, and death, when compared to SOC alone (the control arm).

Interventions

  • OTHER SOC
  • DEVICE nVNS

Trial Details

FieldValue
Enrollment Target 3 participants
Start Date 2021-08-04
Est. Completion 2025-03-01
Phase NA

What the Registry Record Tells You About NCT04935697

The ClinicalTrials.gov registry entry for NCT04935697 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 3 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute), which has 34 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 2 interventions - of which SOC is the first listed.

NCT04935697 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT04935697 about?

NCT04935697 is a clinical study titled "Non-invasive Vagal Neurostimulation (nVNS) for Traumatic Brain Injury (TBI)-Induced Acute Respiratory Distress". This is a prospective, randomized, two-arm, controlled 30-day investigational pilot trial using the gammaCore Sapphire S non-invasive vagus nerve stimulation (nVNS) device + standard of care (SOC) in newly-hospitalized patients with mild-to-moderate traumatic brain injury (TBI) to prevent the progre...

What is the current status of trial NCT04935697?

This trial is currently completed. It is a NA study. The enrollment target is 3 participants. The study started on 2021-08-04. Estimated completion is 2025-03-01.

What interventions are being tested in trial NCT04935697?

The interventions under investigation include: SOC (OTHER), nVNS (DEVICE).

Who is sponsoring clinical trial NCT04935697?

This trial is sponsored by Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute), which has 34 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.