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NCT04931836 · ClinicalTrials.gov registry record · NA
The Influence of Physical Activity on the Gut Microbiome of Pre-Diabetic Adults
A NA study, sponsored by University of Minnesota.
- Completed
- Registry status
- NA
- Development phase
- 77
- Enrollment target
NCT04931836: Completed NA study, sponsored by University of Minnesota.
NCT04931836 is a NA study that has completed, run by University of Minnesota. The registered enrollment target is 77 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (95% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04931836, a NA study, has completed, sponsored by University of Minnesota.
- COMPLETED
- Registry status
- NA
- Development phase
- 77 participants
- Enrollment target
Study Summary
The present study is a 100-participant randomized controlled 2-arm parallel trial that employs a metagenomic approach to examine how 8 weeks of supervised moderate-intensity treadmill walking exercise (MWE) for 30-45 min 3 times/week alters the gut microbiome, serum short chain fatty acids, and the cardiometabolic profile, body weight, and body composition of individuals 30-64 years old who have overweight or obesity and have prediabetes.
Primary Outcome
Changes to the gut microbiome will be assessed via metagenomic sequencing, from pre- to post-intervention. The Shannon Index-a measure of microbial community diversity-will be the primary indicator for changes in gut microbiota composition, and will be assessed at baseline, and following the 4th and 8th weeks. Index values are unitless and range from 0 to 1. Lower values indicate more diversity while higher values indicate less diversity. Outcome will be reported at baseline, 4 weeks, and 8 week
Interventions
- BEHAVIORAL Physical Activity Intervention
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 77 participants |
| Start Date | 2021-07-29 |
| Est. Completion | 2023-11-30 |
| Phase | NA |
What the finished NCT04931836 record still lists
NCT04931836 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 77 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (95% lower).
The record links to 0 conditions, and to 1 intervention - of which Physical Activity Intervention is the first listed.
NCT04931836 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04931836 about?
NCT04931836 is a clinical study titled "The Influence of Physical Activity on the Gut Microbiome of Pre-Diabetic Adults". The present study is a 100-participant randomized controlled 2-arm parallel trial that employs a metagenomic approach to examine how 8 weeks of supervised moderate-intensity treadmill walking exercise (MWE) for 30-45 min 3 times/week alters the gut microbiome, serum short chain fatty acids, and the ...
What is the current status of trial NCT04931836?
This trial is currently completed. It is a NA study. The enrollment target is 77 participants. The study started on 2021-07-29. Estimated completion is 2023-11-30.
What interventions are being tested in trial NCT04931836?
The interventions under investigation include: Physical Activity Intervention (BEHAVIORAL).
Who is sponsoring clinical trial NCT04931836?
This trial is sponsored by University of Minnesota, which has 966 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04931836's enrollment target sits among peer trials
77 1062nd of 2000 higher than 939 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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