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A Study of Guselkumab Administered Subcutaneously in Bio-naive Participants With Active Psoriatic Arthritis Axial Disease
NCT04929210 · View on ClinicalTrials.gov ↗
Study Summary
The purpose of this study is to evaluate the efficacy of guselkumab treatment in participants with active psoriatic arthritis (PsA) axial disease by assessing reduction in axial symptoms and inflammation.
Conditions Studied
Interventions
- DRUG Placebo
- DRUG Guselkumab
Study Locations (20)
Arizona
- Arizona Arthritis and Rheumatology Research PLLC — Avondale
- Arizona Arthritis & Rheumatology Research, PLLC — Chandler
- Arizona Arthritis and Rheumatology Research PLLC — Mesa
- Arizona Arthritis Research, PLC. — Phoenix
- Arizona Arthritis and Rheumatology Associates — Sun City
- Southern Arizona VA Healthcare System — Tucson
California
- Kaiser Permanent Medical Center — Fontana
- Newport Huntington Medical Group — Huntington Beach
- University Of California San Diego — La Jolla
- Rheumatology Center of San Diego — San Diego
Florida
- Bay Pines VA Healthcare System — Bay Pines
- Integral Rheumatology And Immunology Specialists — Plantation
- Florida Medical Clinic, P.A. — Zephyrhills
Illinois
- Great Lakes Clinical Trials — Chicago
- OrthoIllinois — Rockford
- Willow Rheumatology and Wellness — Willowbrook
Maryland
- Johns Hopkins Bayview Medical — Baltimore
- Klein And Associates M D P A — Hagerstown
Arkansas
- Unity Health-White County Medical Center — Searcy
Connecticut
- Clinical Research Center of Connecticut — Danbury
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 411 participants |
| Start Date | 2021-08-30 |
| Est. Completion | 2027-04-13 |
| Phase | Phase 4 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT04929210
The ClinicalTrials.gov registry entry for NCT04929210 describes a study currently listed as active not recruiting. It is categorized as Phase 4, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 411 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Janssen Research & Development, which has 442 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 1 condition, with Arthritis, Psoriatic appearing as the primary indexed condition, and to 2 interventions — of which Placebo is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT04929210 reports 20 study locations spanning 7 distinct geographic areas — top geographies include Arizona, California, Florida. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT04929210 about?
NCT04929210 is a clinical study titled "A Study of Guselkumab Administered Subcutaneously in Bio-naive Participants With Active Psoriatic Arthritis Axial Disease". The purpose of this study is to evaluate the efficacy of guselkumab treatment in participants with active psoriatic arthritis (PsA) axial disease by assessing reduction in axial symptoms and inflammation.
What is the current status of trial NCT04929210?
This trial is currently active not recruiting. It is a Phase 4 study. The enrollment target is 411 participants. The study started on 2021-08-30. Estimated completion is 2027-04-13.
What conditions does trial NCT04929210 study?
This clinical trial studies the following conditions: Arthritis, Psoriatic. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT04929210?
The interventions under investigation include: Placebo (DRUG), Guselkumab (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT04929210?
This trial is sponsored by Janssen Research & Development, which has 442 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT04929210 being conducted?
This trial has 20 study locations across Arizona, Arkansas, California, Connecticut, Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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