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NCT04929015 · ClinicalTrials.gov registry record · NA

Peritoneal Carcinomatosis Leveraging ctDNA Guided Treatment in GI Cancer Study (PERICLES Study)

A NA study of Peritoneal Carcinomatosis and Liver and Intrahepatic Bile Duct Carcinoma, sponsored by Rutgers, The State University of New Jersey.

Recruiting
Registry status
NA
Development phase
30
Enrollment target
2
Study locations

NCT04929015 is a NA study of Peritoneal Carcinomatosis and Liver and Intrahepatic Bile Duct Carcinoma that is actively recruiting participants, run by Rutgers, The State University of New Jersey. The registered enrollment target is 30 participants, below the 58-participant average among 14 other Peritoneal Carcinomatosis trials with a reported enrollment target (48% lower). The trial reports 2 study locations across 1 state.

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The verdict

NCT04929015, a NA study of Peritoneal Carcinomatosis and Liver and Intrahepatic Bile Duct Carcinoma, is actively recruiting participants, sponsored by Rutgers, The State University of New Jersey.

RECRUITING
Registry status
NA
Development phase
30 participants
Enrollment target
2
Study locations

Study Summary

This clinical trial collects biospecimen samples to create a personalized ctDNA test to guide treatment for patients with gastrointestinal cancer with peritoneal carcinomatosis. Deoxyribonucleic acid, or DNA, is the material that carries all the information about how a living thing will work and function. Everyone is born with the same DNA in all our cells throughout our body. Sometimes, some of the cells in the body develop abnormalities in the DNA that cause those cells to grow abnormally and uncontrollably. Cancer occurs when there is abnormal and uncontrolled growth of cells. The DNA in cancer cells is therefore different from the DNA someone is born with. The Signatera ctDNA assay is a laboratory test that takes tumor (cancer) tissue and evaluates it for unique tumor DNA. This evaluation is used to create a report (otherwise known as an assay) personalized to each person's cancer. The personalized assay creates a personalized blood test to detect the level of abnormal DNA from the cancer that may be circulating in the body. Once this personalized blood assay is designed, it may be used to monitor a person's blood for the presence of ctDNA, which will indicate the presence or absence of cancer over time, even after treatment.

Interventions

  • OTHER Electronic Health Record Review
  • PROCEDURE Biospecimen Collection - blood and tissue sample collection

Study Locations (2)

New Jersey

  • RWJBarnabas Health - Cooperman Barnabas, Livingston - Livingston
  • Rutgers Cancer Institute of New Jersey - New Brunswick

Trial Details

FieldValue
Enrollment Target 30 participants
Start Date 2021-04-29
Est. Completion 2024-11-01
Phase NA

What the Registry Record Tells You About NCT04929015

The ClinicalTrials.gov registry entry for NCT04929015 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 30 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 58-participant average among 14 other Peritoneal Carcinomatosis trials with a reported enrollment target (48% lower). The listed sponsor is Rutgers, The State University of New Jersey, which has 413 total studies on file at ClinicalTrials.gov.

The record links to 7 conditions, with Peritoneal Carcinomatosis appearing as the primary indexed condition, and to 2 interventions - of which Electronic Health Record Review is the first listed.

NCT04929015 reports 2 study locations spanning 1 distinct geographic area - top geographies include New Jersey.

Frequently Asked Questions

What is clinical trial NCT04929015 about?

NCT04929015 is a clinical study titled "Peritoneal Carcinomatosis Leveraging ctDNA Guided Treatment in GI Cancer Study (PERICLES Study)". This clinical trial collects biospecimen samples to create a personalized ctDNA test to guide treatment for patients with gastrointestinal cancer with peritoneal carcinomatosis. Deoxyribonucleic acid, or DNA, is the material that carries all the information about how a living thing will work and fun...

What is the current status of trial NCT04929015?

This trial is currently recruiting. It is a NA study. The enrollment target is 30 participants. The study started on 2021-04-29. Estimated completion is 2024-11-01.

What conditions does trial NCT04929015 study?

This clinical trial studies the following conditions: Peritoneal Carcinomatosis, Liver and Intrahepatic Bile Duct Carcinoma, Digestive System Neoplasm, Appendix Carcinoma by AJCC V8 Stage, Colorectal Carcinoma by AJCC V8 Stage.

What interventions are being tested in trial NCT04929015?

The interventions under investigation include: Electronic Health Record Review (OTHER), Biospecimen Collection - blood and tissue sample collection (PROCEDURE).

Who is sponsoring clinical trial NCT04929015?

This trial is sponsored by Rutgers, The State University of New Jersey, which has 413 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT04929015 being conducted?

This trial has 2 study locations across New Jersey. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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