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NCT04927663 · ClinicalTrials.gov registry record · Phase 1
11C-YJH08 PET Imaging for Detection of Glucocorticoid Receptor Expression
A Phase 1 study, sponsored by Rahul Aggarwal.
- Terminated
- Registry status
- Phase 1
- Development phase
- 2
- Enrollment target
NCT04927663 is a Phase 1 study that was terminated before completion, run by Rahul Aggarwal. The registered enrollment target is 2 participants.
The verdict
NCT04927663, a Phase 1 study, was terminated before completion, sponsored by Rahul Aggarwal.
- TERMINATED
- Registry status
- Phase 1
- Development phase
- 2 participants
- Enrollment target
Study Summary
This phase I trial studies if positron emission tomography (PET) imaging using 11C-YJH08 can be useful for detecting certain cell receptor expression in tumor cells in patients with cancer that has spread to other parts of the body (metastatic). 11C-YJH08 is a small-molecule radiotracer that binds to receptors on cells (glucocorticoid receptor) so that they show up better on the PET scan. Systemic therapy (including enzalutamide) can cause more glucocorticoid receptors to be produced in tumor cells, which can make the tumor cells resist hormone therapies. If researchers can find a better way to detect whether glucocorticoid receptors are increasing during therapy, it may lead to more successful therapies using glucocorticoid receptor antagonists.
Interventions
- PROCEDURE Computed Tomography
- PROCEDURE Magnetic Resonance Imaging
- PROCEDURE Positron Emission Tomography
- DRUG 11C-YJH08
- PROCEDURE Optional Tumor Biopsy
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 2 participants |
| Start Date | 2021-08-10 |
| Est. Completion | 2025-02-28 |
| Phase | Phase 1 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT04927663
The ClinicalTrials.gov registry entry for NCT04927663 describes a study currently listed as terminated, categorized as Phase 1. The registered enrollment target is 2 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Rahul Aggarwal, which has 13 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 5 interventions - of which Computed Tomography is the first listed.
NCT04927663 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT04927663 about?
NCT04927663 is a clinical study titled "11C-YJH08 PET Imaging for Detection of Glucocorticoid Receptor Expression". This phase I trial studies if positron emission tomography (PET) imaging using 11C-YJH08 can be useful for detecting certain cell receptor expression in tumor cells in patients with cancer that has spread to other parts of the body (metastatic). 11C-YJH08 is a small-molecule radiotracer that binds t...
What is the current status of trial NCT04927663?
This trial is currently terminated. It is a Phase 1 study. The enrollment target is 2 participants. The study started on 2021-08-10. Estimated completion is 2025-02-28.
What interventions are being tested in trial NCT04927663?
The interventions under investigation include: Computed Tomography (PROCEDURE), Magnetic Resonance Imaging (PROCEDURE), Positron Emission Tomography (PROCEDURE), 11C-YJH08 (DRUG), Optional Tumor Biopsy (PROCEDURE).
Who is sponsoring clinical trial NCT04927663?
This trial is sponsored by Rahul Aggarwal, which has 13 total clinical trials registered on ClinicalTrials.gov.
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