Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT04925453 · ClinicalTrials.gov registry record · NA
tDCS and Cognitive Training in Active Duty Service Members With Mild TBI: A Pilot Study
A NA study, sponsored by United States Naval Medical Center, San Diego.
- Completed
- Registry status
- NA
- Development phase
- 56
- Enrollment target
NCT04925453: Completed NA study, sponsored by United States Naval Medical Center, San Diego.
NCT04925453 is a NA study that has completed, run by United States Naval Medical Center, San Diego. The registered enrollment target is 56 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (96% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04925453, a NA study, has completed, sponsored by United States Naval Medical Center, San Diego.
- COMPLETED
- Registry status
- NA
- Development phase
- 56 participants
- Enrollment target
Study Summary
The proposed study will evaluate a new approach to cognitive rehabilitation of mild traumatic brain injury (mTBI) using a brain stimulation technique called transcranial direct current stimulation (tDCS). Specifically, we will investigate how tDCS combined with cognitive training improves deficits to attention and working memory in Active Duty Service Members with a history of mild traumatic brain injury (TBI). Measures of attention-related brain activity, neurocognitive assessments, and self-reported clinical outcomes will be used to determine effects of tDCS vs. sham tDCS when paired with a cognitive training intervention. By doing this study, we hope to find a reliable, noninvasive, and efficient method of treating mild TBI cognitive symptoms.
Primary Outcome
Standardized neuropsychological assessment measure of visual attention and working memory
Interventions
- COMBINATION_PRODUCT active tDCS and cognitive training intervention
- COMBINATION_PRODUCT sham tDCS and cognitive training intervention
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 56 participants |
| Start Date | 2021-01-19 |
| Est. Completion | 2025-07-30 |
| Phase | NA |
What the finished NCT04925453 record still lists
NCT04925453 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 56 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (96% lower).
The record links to 0 conditions, and to 2 interventions - of which active tDCS and cognitive training intervention is the first listed.
NCT04925453 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04925453 about?
NCT04925453 is a clinical study titled "tDCS and Cognitive Training in Active Duty Service Members With Mild TBI: A Pilot Study". The proposed study will evaluate a new approach to cognitive rehabilitation of mild traumatic brain injury (mTBI) using a brain stimulation technique called transcranial direct current stimulation (tDCS). Specifically, we will investigate how tDCS combined with cognitive training improves deficits t...
What is the current status of trial NCT04925453?
This trial is currently completed. It is a NA study. The enrollment target is 56 participants. The study started on 2021-01-19. Estimated completion is 2025-07-30.
What interventions are being tested in trial NCT04925453?
The interventions under investigation include: active tDCS and cognitive training intervention (COMBINATION_PRODUCT), sham tDCS and cognitive training intervention (COMBINATION_PRODUCT).
Who is sponsoring clinical trial NCT04925453?
This trial is sponsored by United States Naval Medical Center, San Diego, which has 41 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04925453's enrollment target sits among peer trials
56 1262nd of 2000 higher than 737 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT02287428 · 56 participants · Phase 1
Personalized NeoAntigen Cancer Vaccine w RT Plus Pembrolizumab for Patients With Newly Diagnosed GBM
- NCT02923011 · 56 participants · Phase 3
Comparative Effectiveness of MRgFUS Versus CTgRFA for Osteoid Osteomas
- NCT02935283 · 56 participants
Neuroimaging and Neuropsychological Outcomes in Urea Cycle Disorders
- NCT03375866 · 56 participants · NA
Effects of Mixed Nut Consumption on Satiety and Weight Management
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI