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NCT04924140 · ClinicalTrials.gov registry record · Phase 1

A Study to Assess Absolute Bioavailability of Aducanumab in Healthy Volunteers

A Phase 1 study, sponsored by Biogen.

Completed
Registry status
Phase 1
Development phase
30
Enrollment target

NCT04924140 is a Phase 1 study that has completed, run by Biogen. The registered enrollment target is 30 participants.

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The verdict

NCT04924140, a Phase 1 study, has completed, sponsored by Biogen.

COMPLETED
Registry status
Phase 1
Development phase
30 participants
Enrollment target

Study Summary

The primary objective of this study is to evaluate the absolute bioavailability of a single, fixed subcutaneous (SC) dose of aducanumab compared with a single weight-based intravenous (IV) dose of aducanumab in healthy volunteers. The secondary objectives of this study are to assess the safety and tolerability of aducanumab administered SC in healthy volunteers and to characterize additional pharmacokinetic (PK) parameters of a single, fixed SC dose of aducanumab and a weight-based IV dose of aducanumab in healthy volunteers.

Interventions

  • DRUG Aducanumab

Trial Details

FieldValue
Enrollment Target 30 participants
Start Date 2021-06-30
Est. Completion 2021-10-01
Phase Phase 1

Sponsor

Biogen

334 total trials

What the Registry Record Tells You About NCT04924140

The ClinicalTrials.gov registry entry for NCT04924140 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 30 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Biogen, which has 334 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 1 intervention - of which Aducanumab is the first listed.

NCT04924140 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT04924140 about?

NCT04924140 is a clinical study titled "A Study to Assess Absolute Bioavailability of Aducanumab in Healthy Volunteers". The primary objective of this study is to evaluate the absolute bioavailability of a single, fixed subcutaneous (SC) dose of aducanumab compared with a single weight-based intravenous (IV) dose of aducanumab in healthy volunteers. The secondary objectives of this study are to assess the safety and ...

What is the current status of trial NCT04924140?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 30 participants. The study started on 2021-06-30. Estimated completion is 2021-10-01.

What interventions are being tested in trial NCT04924140?

The interventions under investigation include: Aducanumab (DRUG).

Who is sponsoring clinical trial NCT04924140?

This trial is sponsored by Biogen, which has 334 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.