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NCT04924114 · ClinicalTrials.gov registry record · Phase 1
A Study of MK-6194 (PT101) in Participants With Active Ulcerative Colitis (UC) (MK-6194-002)
A Phase 1 study, sponsored by Merck Sharp & Dohme.
- Completed
- Registry status
- Phase 1
- Development phase
- 57
- Enrollment target
NCT04924114: Completed Phase 1 study, sponsored by Merck Sharp & Dohme.
NCT04924114 is a Phase 1 study that has completed, run by Merck Sharp & Dohme. The registered enrollment target is 57 participants, roughly in line with the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04924114, a Phase 1 study, has completed, sponsored by Merck Sharp & Dohme.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 57 participants
- Enrollment target
Study Summary
The purpose of this study is to evaluate the safety, tolerability, pharmacokinetics, pharmacodynamics and immunogenicity of MK-6194 in participants with active UC.
Primary Outcome
An AE is any untoward medical occurrence in a clinical study participant, temporally associated with the use of study intervention, whether or not considered related to the study intervention.
Interventions
- DRUG MK-6194
- DRUG MK-6194-matching placebo
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 57 participants |
| Start Date | 2021-10-14 |
| Est. Completion | 2024-07-15 |
| Phase | Phase 1 |
What the finished NCT04924114 record still lists
NCT04924114 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 57 participants, a relatively small participant target, roughly in line with the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target.
The record links to 0 conditions, and to 2 interventions - of which MK-6194 is the first listed.
NCT04924114 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04924114 about?
NCT04924114 is a clinical study titled "A Study of MK-6194 (PT101) in Participants With Active Ulcerative Colitis (UC) (MK-6194-002)". The purpose of this study is to evaluate the safety, tolerability, pharmacokinetics, pharmacodynamics and immunogenicity of MK-6194 in participants with active UC.
What is the current status of trial NCT04924114?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 57 participants. The study started on 2021-10-14. Estimated completion is 2024-07-15.
What interventions are being tested in trial NCT04924114?
The interventions under investigation include: MK-6194 (DRUG), MK-6194-matching placebo (DRUG).
Who is sponsoring clinical trial NCT04924114?
This trial is sponsored by Merck Sharp & Dohme, which has 558 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04924114's enrollment target sits among peer trials
57 901st of 2000 higher than 1,099 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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