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NCT04923477 · ClinicalTrials.gov registry record · NA
Therapeutic Exercise for Rotator Cuff Tendinopathy / Subacromial Pain Syndrome - Outcomes and Mechanisms
A NA study of Rotator Cuff Injuries and Rotator Cuff Tendinitis, sponsored by University of Southern California.
- Recruiting
- Registry status
- NA
- Development phase
- 60
- Enrollment target
- 1
- Study location
NCT04923477: Recruiting NA study of Rotator Cuff Injuries and Rotator Cuff Tendinitis, sponsored by University of Southern California.
NCT04923477 is a NA study of Rotator Cuff Injuries and Rotator Cuff Tendinitis that is actively recruiting participants, run by University of Southern California. The registered enrollment target is 60 participants, below the 95-participant average among 10 other Rotator Cuff Injuries trials with a reported enrollment target (37% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04923477, a NA study of Rotator Cuff Injuries and Rotator Cuff Tendinitis, is actively recruiting participants, sponsored by University of Southern California.
- RECRUITING
- Registry status
- NA
- Development phase
- 60 participants
- Enrollment target
- 1
- Study location
Study Summary
Rotator cuff tendinopathy, one of the pathologies identified as part of the cluster of shoulder symptoms known as subacromial pain syndrome, is a common musculoskeletal shoulder condition. Resolution of pain and disability is poor despite treatment, with only about 50% reporting full recovery at 12 - 18 months. Prior studies suggest therapeutic exercise when used alone and with other interventions can have positive outcomes; however, not all patients with rotator cuff tendinopathy respond. Few studies have assessed the effects of exercise for individuals with chronic pain, especially brain driven mechanisms, thought to play a key role. In this study, we will use brain imaging to understand the mechanisms, identify predictors of a positive response to exercise, and the relationship to biomechanical and pain-related factors in patients with RC tendinopathy. The findings from this study will optimize the delivery and treatment response to exercise for individuals with shoulder pain.
Primary Outcome
The PENN is a self-report measure of pain, satisfaction with shoulder use, and function. The pain section has 3 questions of pain at rest, with normal daily activities, and with strenuous activities. The disability section has 20 items rated on a 4-category Likert scale for difficulty (0=cannot do at all, 1=much difficulty, 2=some difficulty, 3=no difficulty, and x=did not do before injury). The satisfaction section is 1 question, rating satisfaction with shoulder use on a 0-10 numeric scale (1
Conditions Studied
Interventions
- OTHER Therapeutic Exercise for Rotator Cuff Tendinopathy / Subacromial Pain Syndrome
Study Locations (1)
California
- Clinical Biomechanics Orthopedic and Sports Outcomes Research Laboratory - Los Angeles
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 60 participants |
| Start Date | 2021-06-08 |
| Est. Completion | 2026-12-31 |
| Phase | NA |
What NCT04923477 shows while recruiting
NCT04923477 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 60 participants, a relatively small participant target, below the 95-participant average among 10 other Rotator Cuff Injuries trials with a reported enrollment target (37% lower).
The record links to 4 conditions, with Rotator Cuff Injuries appearing as the primary indexed condition, and to 1 intervention - of which Therapeutic Exercise for Rotator Cuff Tendinopathy / Subacromial Pain Syndrome is the first listed.
NCT04923477 reports a single indexed study location in California.
Frequently Asked Questions
What is clinical trial NCT04923477 about?
NCT04923477 is a clinical study titled "Therapeutic Exercise for Rotator Cuff Tendinopathy / Subacromial Pain Syndrome - Outcomes and Mechanisms". Rotator cuff tendinopathy, one of the pathologies identified as part of the cluster of shoulder symptoms known as subacromial pain syndrome, is a common musculoskeletal shoulder condition. Resolution of pain and disability is poor despite treatment, with only about 50% reporting full recovery at 12 ...
What is the current status of trial NCT04923477?
This trial is currently recruiting. It is a NA study. The enrollment target is 60 participants. The study started on 2021-06-08. Estimated completion is 2026-12-31.
What conditions does trial NCT04923477 study?
This clinical trial studies the following conditions: Rotator Cuff Injuries, Rotator Cuff Tendinitis, Rotator Cuff Tendinosis, Subacromial Pain Syndrome.
What interventions are being tested in trial NCT04923477?
The interventions under investigation include: Therapeutic Exercise for Rotator Cuff Tendinopathy / Subacromial Pain Syndrome (OTHER).
Who is sponsoring clinical trial NCT04923477?
This trial is sponsored by University of Southern California, which has 617 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04923477 being conducted?
This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT04923477's enrollment target sits among peer trials
60 7th of 10 higher than 3 of 10 other Rotator Cuff Injuries trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Rotator Cuff Injuries trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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