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NCT04920786 · ClinicalTrials.gov registry record · Phase 1
Sequential Dose-escalation Study to Assess the Safety, Tolerability and Pharmacokinetics of TB006 in Healthy Subjects
A Phase 1 study, sponsored by TrueBinding.
- Completed
- Registry status
- Phase 1
- Development phase
- 48
- Enrollment target
NCT04920786: Completed Phase 1 study, sponsored by TrueBinding.
NCT04920786 is a Phase 1 study that has completed, run by TrueBinding. The registered enrollment target is 48 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (20% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04920786, a Phase 1 study, has completed, sponsored by TrueBinding.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 48 participants
- Enrollment target
Study Summary
This is a single dose, dose-escalation study to assess the safety, tolerability, pharmacokinetics and pharmacodynamics of TB006, a monoclonal antibody that will be studied as a disease modifying treatment for Alzheimer's disease.
Primary Outcome
To measure the incidence of AEs and SAEs, clinical laboratory parameters, and vital signs until Day 75 after dosing.
Interventions
- DRUG TB006
- OTHER Sterile saline (Placebo)
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 48 participants |
| Start Date | 2021-06-01 |
| Est. Completion | 2022-05-03 |
| Phase | Phase 1 |
What the finished NCT04920786 record still lists
NCT04920786 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 48 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (20% lower).
The record links to 0 conditions, and to 2 interventions - of which TB006 is the first listed.
NCT04920786 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04920786 about?
NCT04920786 is a clinical study titled "Sequential Dose-escalation Study to Assess the Safety, Tolerability and Pharmacokinetics of TB006 in Healthy Subjects". This is a single dose, dose-escalation study to assess the safety, tolerability, pharmacokinetics and pharmacodynamics of TB006, a monoclonal antibody that will be studied as a disease modifying treatment for Alzheimer's disease.
What is the current status of trial NCT04920786?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 48 participants. The study started on 2021-06-01. Estimated completion is 2022-05-03.
What interventions are being tested in trial NCT04920786?
The interventions under investigation include: TB006 (DRUG), Sterile saline (Placebo) (OTHER).
Who is sponsoring clinical trial NCT04920786?
This trial is sponsored by TrueBinding, which has 4 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04920786's enrollment target sits among peer trials
48 1025th of 2000 higher than 948 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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