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NCT04919642 · ClinicalTrials.gov registry record · Phase 2
Study to Evaluate the Efficacy and Safety of TT-00420 (Tinengotinib) in Cholangiocarcinoma
A Phase 2 study, sponsored by TransThera Sciences (Nanjing).
- Completed
- Registry status
- Phase 2
- Development phase
- 55
- Enrollment target
NCT04919642: Completed Phase 2 study, sponsored by TransThera Sciences (Nanjing).
NCT04919642 is a Phase 2 study that has completed, run by TransThera Sciences (Nanjing). The registered enrollment target is 55 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (59% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04919642, a Phase 2 study, has completed, sponsored by TransThera Sciences (Nanjing).
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 55 participants
- Enrollment target
Study Summary
This study is an open-label, multicenter study to evaluate the efficacy and safety of TT-00420 tablet in adult patients with advanced cholangiocarcinoma.
Primary Outcome
The proportion of subjects who achieved a complete response (CR) or a partial response (PR) based on RECIST version 1.1.
Interventions
- DRUG TT-00420
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 55 participants |
| Start Date | 2021-12-07 |
| Est. Completion | 2024-02-28 |
| Phase | Phase 2 |
What the finished NCT04919642 record still lists
NCT04919642 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 55 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (59% lower).
The record links to 0 conditions, and to 1 intervention - of which TT-00420 is the first listed.
NCT04919642 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04919642 about?
NCT04919642 is a clinical study titled "Study to Evaluate the Efficacy and Safety of TT-00420 (Tinengotinib) in Cholangiocarcinoma". This study is an open-label, multicenter study to evaluate the efficacy and safety of TT-00420 tablet in adult patients with advanced cholangiocarcinoma.
What is the current status of trial NCT04919642?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 55 participants. The study started on 2021-12-07. Estimated completion is 2024-02-28.
What interventions are being tested in trial NCT04919642?
The interventions under investigation include: TT-00420 (DRUG).
Who is sponsoring clinical trial NCT04919642?
This trial is sponsored by TransThera Sciences (Nanjing), which has 7 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04919642's enrollment target sits among peer trials
55 1153rd of 2000 higher than 841 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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