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NCT04908683 · ClinicalTrials.gov registry record · Phase 3

A Study of an Adenovirus Serotype 26 Pre-fusion Conformation-stabilized F Protein (Ad26. RSV. preF) Based Respiratory Syncytial Virus (RSV) Vaccine in the Prevention of Lower Respiratory Tract Disease in Adults Aged 60 Years and Older

A Phase 3 study, sponsored by Janssen Vaccines & Prevention B.V..

Completed
Registry status
Phase 3
Development phase
25,236
Enrollment target

NCT04908683 is a Phase 3 study that has completed, run by Janssen Vaccines & Prevention B.V.. The registered enrollment target is 25,236 participants.

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The verdict

NCT04908683, a Phase 3 study, has completed, sponsored by Janssen Vaccines & Prevention B.V..

COMPLETED
Registry status
Phase 3
Development phase
25,236 participants
Enrollment target

Study Summary

The study will enroll up to 27,200 participants in order to demonstrate the efficacy of the active Ad26.RSV.preF-based study vaccine in the prevention of Reverse Transcription Polymerase Chain Reaction (RT-PCR) confirmed Respiratory Syncytial Virus (RSV)-mediated Lower Respiratory Tract Disease (LRTD) when compared to placebo in adults aged 60 years and above.

Interventions

  • BIOLOGICAL Placebo
  • BIOLOGICAL Adenovirus serotype 26 (Ad26)-based respiratory syncytial virus (RSV). preF

Trial Details

FieldValue
Enrollment Target 25,236 participants
Start Date 2021-07-21
Est. Completion 2023-07-21
Phase Phase 3

Sponsor

Janssen Vaccines & Prevention B.V.

34 total trials

What the Registry Record Tells You About NCT04908683

The ClinicalTrials.gov registry entry for NCT04908683 describes a study currently listed as completed, categorized as Phase 3. The registered enrollment target is 25,236 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Janssen Vaccines & Prevention B.V., which has 34 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.

NCT04908683 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT04908683 about?

NCT04908683 is a clinical study titled "A Study of an Adenovirus Serotype 26 Pre-fusion Conformation-stabilized F Protein (Ad26. RSV. preF) Based Respiratory Syncytial Virus (RSV) Vaccine in the Prevention of Lower Respiratory Tract Disease in Adults Aged 60 Years and Older". The study will enroll up to 27,200 participants in order to demonstrate the efficacy of the active Ad26.RSV.preF-based study vaccine in the prevention of Reverse Transcription Polymerase Chain Reaction (RT-PCR) confirmed Respiratory Syncytial Virus (RSV)-mediated Lower Respiratory Tract Disease (LRT...

What is the current status of trial NCT04908683?

This trial is currently completed. It is a Phase 3 study. The enrollment target is 25,236 participants. The study started on 2021-07-21. Estimated completion is 2023-07-21.

What interventions are being tested in trial NCT04908683?

The interventions under investigation include: Placebo (BIOLOGICAL), Adenovirus serotype 26 (Ad26)-based respiratory syncytial virus (RSV). preF (BIOLOGICAL).

Who is sponsoring clinical trial NCT04908683?

This trial is sponsored by Janssen Vaccines & Prevention B.V., which has 34 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.