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NCT04904120 · ClinicalTrials.gov registry record · Phase 1
Targeted Imaging of Melanoma for Alpha-Particle Radiotherapy
A Phase 1 study, sponsored by Perspective Therapeutics.
- Completed
- Registry status
- Phase 1
- Development phase
- 7
- Enrollment target
NCT04904120: Completed Phase 1 study, sponsored by Perspective Therapeutics.
NCT04904120 is a Phase 1 study that has completed, run by Perspective Therapeutics. The registered enrollment target is 7 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (88% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04904120, a Phase 1 study, has completed, sponsored by Perspective Therapeutics.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 7 participants
- Enrollment target
Study Summary
The study hypothesis is that new imaging agents \[203Pb\]VMT01 and \[68Ga\]VMT02 can be safely used in humans without independent biological effect and can be used to image melanoma tumors expressing the melanocortin sub-type 1 receptor (MC1R) by SPECT/CT and PET/CT imaging modalities respectively.
Primary Outcome
Adverse Events (AEs) will be assessed for severity according to CTCAE v5.0 and for relatedness to each of the investigative imaging agents (\[203Pb\]VMT01 and \[68Ga\]VMT02). Assessments attributed as possibly, probably, or definitely related to the imaging agent will be considered related.
Interventions
- DRUG [203Pb]VMT01
- DRUG [68Ga]VMT02
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 7 participants |
| Start Date | 2021-03-05 |
| Est. Completion | 2022-09-20 |
| Phase | Phase 1 |
What the finished NCT04904120 record still lists
NCT04904120 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 7 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (88% lower).
The record links to 0 conditions, and to 2 interventions - of which [203Pb]VMT01 is the first listed.
NCT04904120 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04904120 about?
NCT04904120 is a clinical study titled "Targeted Imaging of Melanoma for Alpha-Particle Radiotherapy". The study hypothesis is that new imaging agents \[203Pb\]VMT01 and \[68Ga\]VMT02 can be safely used in humans without independent biological effect and can be used to image melanoma tumors expressing the melanocortin sub-type 1 receptor (MC1R) by SPECT/CT and PET/CT imaging modalities respectively.
What is the current status of trial NCT04904120?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 7 participants. The study started on 2021-03-05. Estimated completion is 2022-09-20.
What interventions are being tested in trial NCT04904120?
The interventions under investigation include: [203Pb]VMT01 (DRUG), [68Ga]VMT02 (DRUG).
Who is sponsoring clinical trial NCT04904120?
This trial is sponsored by Perspective Therapeutics, which has 4 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04904120's enrollment target sits among peer trials
7 1972nd of 2000 higher than 27 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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