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NCT04903366 · ClinicalTrials.gov registry record
Absorption and Safety of Topical Timolol to Treat Chronic Wounds
A clinical trial, sponsored by VA Northern California Health Care System.
- Completed
- Registry status
- 40
- Enrollment target
NCT04903366: Completed study, sponsored by VA Northern California Health Care System.
NCT04903366 is a clinical trial that has completed, run by VA Northern California Health Care System. The registered enrollment target is 40 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04903366 has completed, sponsored by VA Northern California Health Care System.
- COMPLETED
- Registry status
- 40 participants
- Enrollment target
Study Summary
Topical timolol has been used primarily as eye drops to treat glaucoma for many years. Recent clinical experience has broadened its off-label use for a number of skin conditions, including slow-healing wounds. While there have been extensive safety studies performed on timolol administration to treat the eye, to date, no studies have documented absorption of timolol after applied on chronic wounds. Thus, the purpose of this study is to determine the blood levels of timolol in patients after topical administration to a chronic wound, and compare these levels with those of patients after administration of the same drug formulation on the eye for the indication of glaucoma.
Primary Outcome
For both groups, after administration of timolol drops as prescribed, one 6 mL blood was drawn. After centrifugation, the plasma from both groups was frozen at -80°C until assay.
Interventions
- DRUG Timolol Maleate
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 40 participants |
| Start Date | 2017-11-21 |
| Est. Completion | 2020-01-14 |
What the finished NCT04903366 record still lists
NCT04903366 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 40 participants, a relatively small participant target.
The record links to 0 conditions, and to 1 intervention - of which Timolol Maleate is the first listed.
NCT04903366 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04903366 about?
NCT04903366 is a clinical study titled "Absorption and Safety of Topical Timolol to Treat Chronic Wounds". Topical timolol has been used primarily as eye drops to treat glaucoma for many years. Recent clinical experience has broadened its off-label use for a number of skin conditions, including slow-healing wounds. While there have been extensive safety studies performed on timolol administration to trea...
What is the current status of trial NCT04903366?
This trial is currently completed. The enrollment target is 40 participants. The study started on 2017-11-21. Estimated completion is 2020-01-14.
What interventions are being tested in trial NCT04903366?
The interventions under investigation include: Timolol Maleate (DRUG).
Who is sponsoring clinical trial NCT04903366?
This trial is sponsored by VA Northern California Health Care System, which has 4 total clinical trials registered on ClinicalTrials.gov.
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