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NCT04898595 · ClinicalTrials.gov registry record · NA
Discontinuing CRRT in Patients with Acute Kidney Injury
A NA study, sponsored by West Virginia University.
- Completed
- Registry status
- NA
- Development phase
- 67
- Enrollment target
NCT04898595: Completed NA study, sponsored by West Virginia University.
NCT04898595 is a NA study that has completed, run by West Virginia University. The registered enrollment target is 67 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (95% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04898595, a NA study, has completed, sponsored by West Virginia University.
- COMPLETED
- Registry status
- NA
- Development phase
- 67 participants
- Enrollment target
Study Summary
In this study, investigators are going to test whether a standardize approach to discontinuation of Continuous Renal Replacement Therapy (CRRT) using a set of criteria improves outcomes. These criteria are based on the best available evidence. In a systematic review, aside from urine output, there was no one factor that predicted successful weaning of RRT in patients with AKI. Urine output prior to discontinuation of RRT was the most commonly described and robust predictor. The pooled analysis found a sensitivity of 66.2% and specificity of 73.6% for urine output to predict successful RRT discontinuation. Patients with AKI on CRRT recruited during the first half of the study will be controls (usual process of care). After accrual, patients recruited for the second half will receive the intervention where discontinuation of CRRT will be guided by a set of criteria based on the patient's hemodynamic status and other factors.
Primary Outcome
Successful discontinuation of CRRT is defined by being free from any form of renal replacement therapy for at least 7 consecutive days. We will measure the difference in the proportion of participants who achieve successful discontinuation of CRRT between the two groups.
Interventions
- PROCEDURE Discontinuation of CRRT
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 67 participants |
| Start Date | 2021-06-01 |
| Est. Completion | 2024-12-12 |
| Phase | NA |
What the finished NCT04898595 record still lists
NCT04898595 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 67 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (95% lower).
The record links to 0 conditions, and to 1 intervention - of which Discontinuation of CRRT is the first listed.
NCT04898595 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04898595 about?
NCT04898595 is a clinical study titled "Discontinuing CRRT in Patients with Acute Kidney Injury". In this study, investigators are going to test whether a standardize approach to discontinuation of Continuous Renal Replacement Therapy (CRRT) using a set of criteria improves outcomes. These criteria are based on the best available evidence. In a systematic review, aside from urine output, there w...
What is the current status of trial NCT04898595?
This trial is currently completed. It is a NA study. The enrollment target is 67 participants. The study started on 2021-06-01. Estimated completion is 2024-12-12.
What interventions are being tested in trial NCT04898595?
The interventions under investigation include: Discontinuation of CRRT (PROCEDURE).
Who is sponsoring clinical trial NCT04898595?
This trial is sponsored by West Virginia University, which has 122 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04898595's enrollment target sits among peer trials
67 1139th of 2000 higher than 862 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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