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NCT04886258 · ClinicalTrials.gov registry record · Phase 2

Study of Efficacy, Safety and Tolerability of DFV890 in Patients With Knee Osteoarthritis

A Phase 2 study of Symptomatic Knee Osteoarthritis, sponsored by Novartis Pharmaceuticals.

Completed
Registry status
Phase 2
Development phase
115
Enrollment target
20
Study locations

NCT04886258 is a Phase 2 study of Symptomatic Knee Osteoarthritis that has completed, run by Novartis Pharmaceuticals. The registered enrollment target is 115 participants. The trial reports 20 study locations across 11 states.

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The verdict

NCT04886258, a Phase 2 study of Symptomatic Knee Osteoarthritis, has completed, sponsored by Novartis Pharmaceuticals.

COMPLETED
Registry status
Phase 2
Development phase
115 participants
Enrollment target
20
Study locations

Study Summary

This was a double-blinded, two-arm, phase 2a study to assess efficacy, safety and tolerability of DFV890 in participants with symptomatic knee osteoarthritis.

Interventions

  • DRUG Placebo
  • DRUG DFV890

Study Locations (20)

Other

  • Novartis Investigative Site - San Miguel de Tucumán
  • Novartis Investigative Site - Nový Jičín
  • Novartis Investigative Site - Prague
  • Novartis Investigative Site - Uherské Hradiště
  • Novartis Investigative Site - Bad Doberan
  • Novartis Investigative Site - Berlin
  • Novartis Investigative Site - Hamburg
  • Novartis Investigative Site - Hamburg
  • Novartis Investigative Site - Leipzig

Florida

  • IRIS Research and Development - Plantation
  • Conquest Research - Winter Park

Arizona

  • ARENSIA Explor Med Res Clinic - Phoenix

California

  • TriWest Reserach Associates - El Cajon

Colorado

  • Skylight Health Res Inc Color Spr - Colorado Springs

Georgia

  • Ctr for Adv Research and Education - Gainesville

Illinois

  • Northwestern University - Chicago

Buenos Aires

  • Novartis Investigative Site - CABA

Trial Details

FieldValue
Enrollment Target 115 participants
Start Date 2021-09-20
Est. Completion 2024-12-23
Phase Phase 2

Sponsor

Novartis Pharmaceuticals

1,375 total trials

What the Registry Record Tells You About NCT04886258

The ClinicalTrials.gov registry entry for NCT04886258 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 115 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Novartis Pharmaceuticals, which has 1,375 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Symptomatic Knee Osteoarthritis appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.

NCT04886258 reports 20 study locations spanning 11 distinct geographic areas - top geographies include Other, Florida, Arizona.

Frequently Asked Questions

What is clinical trial NCT04886258 about?

NCT04886258 is a clinical study titled "Study of Efficacy, Safety and Tolerability of DFV890 in Patients With Knee Osteoarthritis". This was a double-blinded, two-arm, phase 2a study to assess efficacy, safety and tolerability of DFV890 in participants with symptomatic knee osteoarthritis.

What is the current status of trial NCT04886258?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 115 participants. The study started on 2021-09-20. Estimated completion is 2024-12-23.

What conditions does trial NCT04886258 study?

This clinical trial studies the following conditions: Symptomatic Knee Osteoarthritis.

What interventions are being tested in trial NCT04886258?

The interventions under investigation include: Placebo (DRUG), DFV890 (DRUG).

Who is sponsoring clinical trial NCT04886258?

This trial is sponsored by Novartis Pharmaceuticals, which has 1,375 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT04886258 being conducted?

This trial has 20 study locations across Arizona, California, Colorado, Florida, Georgia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.