Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT04880668 · ClinicalTrials.gov registry record · NA

Impact of Aerosol Box Use on Healthcare Provider Contamination

A NA study, sponsored by KidSIM Simulation Program.

Completed
Registry status
NA
Development phase
122
Enrollment target

NCT04880668: Completed NA study, sponsored by KidSIM Simulation Program.

NCT04880668 is a NA study that has completed, run by KidSIM Simulation Program. The registered enrollment target is 122 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (91% lower). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT04880668, a NA study, has completed, sponsored by KidSIM Simulation Program.

COMPLETED
Registry status
NA
Development phase
122 participants
Enrollment target

Study Summary

Aerosol Generating Medical Procedures (AGMP) are procedures that have the potential to create tiny particles suspended in the air. These particles can contain germs such as viruses. The current Coronavirus Disease 2019 (COVID-19) pandemic is caused by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Patients infected with SARS-CoV-2 experience unusually high rates of critical illness that needs advanced airway management and intensive care unit admission. Bag-valve-mask (BVM) ventilation, laryngeal mask airway insertion (LMA), and endotracheal Intubation (ETI) are common AGMP for critically ill COVID-19 patients, and may contribute to a high risk of infection amongst Health Care Workers (HCW). To lessen HCW risk during high-risk AGMPs, a device called an aerosol box has been developed to place over the head of the patient, shielding the provider's face from virus droplets suspended in the air. The purpose of this research study is to better understand how particles disperse during AGMPs. The project team hopes what is learned from the project can help inform infection control measures. This could help make changes to the clinical environment and make it safer for HCW's. The investigators intend to investigate how an aerosol box performs in reducing contamination of HCW's who perform critical airway interventions.

Primary Outcome

Integrated density of HCP contamination, quantified from digital photos of GloGerm™ deposited on the airway team members pre and post-doffing.

Interventions

  • DEVICE Aerosol Box (Splashguard)

Trial Details

FieldValue
Enrollment Target 122 participants
Start Date 2021-06-11
Est. Completion 2021-12-16
Phase NA
KidSIM Simulation Program

3 total trials

What the finished NCT04880668 record still lists

NCT04880668 is an interventional study that assigns participants to a tested intervention. The registered 122 participants enrollment target is mid-sized for trials with a published cap, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (91% lower).

The record links to 0 conditions, and to 1 intervention - of which Aerosol Box (Splashguard) is the first listed.

NCT04880668 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT04880668 about?

NCT04880668 is a clinical study titled "Impact of Aerosol Box Use on Healthcare Provider Contamination". Aerosol Generating Medical Procedures (AGMP) are procedures that have the potential to create tiny particles suspended in the air. These particles can contain germs such as viruses. The current Coronavirus Disease 2019 (COVID-19) pandemic is caused by the novel severe acute respiratory syndrome coro...

What is the current status of trial NCT04880668?

This trial is currently completed. It is a NA study. The enrollment target is 122 participants. The study started on 2021-06-11. Estimated completion is 2021-12-16.

What interventions are being tested in trial NCT04880668?

The interventions under investigation include: Aerosol Box (Splashguard) (DEVICE).

Who is sponsoring clinical trial NCT04880668?

This trial is sponsored by KidSIM Simulation Program, which has 3 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT04880668's enrollment target sits among peer trials

122 762nd of 2000 higher than 1,239 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT03363373 · 122 participants · Phase 2

    Naxitamab for High-Risk Neuroblastoma Patients With Primary Refractory Disease or Incomplete Response to Salvage Treatment in Bone and/or Bone Marrow

  • NCT03463954 · 122 participants · NA

    Confirmatory Clinical Evaluation of Novilase® Laser Therapy for Focal Destruction of Malignant Breast Tumors

  • NCT04503265 · 122 participants · Phase 1

    A Trial of AMXI-5001 for Treatment in Patients With Advanced Malignancies

  • NCT04700527 · 122 participants · Phase 1

    The Effects of SCFA Supplementation in Subjects Receiving Abdominopelvic RT: A Randomized Controlled Study

Similar registry start date

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

  • NCT07125183 · started 2026-12 · Phase 2

    Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma

  • NCT07292298 · started 2026-11 · Phase 2

    Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates

  • NCT04263285 · started 2026-10 · NA

    Treatment of Depression Post-SCI

Source: ClinicalTrials.gov NCT04880668, the US trial registry maintained by the National Library of Medicine. NCT04880668 (mid enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.