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NCT04880031 · ClinicalTrials.gov registry record · Phase 2
A Study of BOS-580 in Obese Subjects at Risk for, or With Biopsy-confirmed, Nonalcoholic Steatohepatitis (NASH) With an Extension
A Phase 2 study, sponsored by GlaxoSmithKline.
- Completed
- Registry status
- Phase 2
- Development phase
- 231
- Enrollment target
NCT04880031: Completed Phase 2 study, sponsored by GlaxoSmithKline.
NCT04880031 is a Phase 2 study that has completed, run by GlaxoSmithKline. The registered enrollment target is 231 participants, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (74% higher). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04880031, a Phase 2 study, has completed, sponsored by GlaxoSmithKline.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 231 participants
- Enrollment target
Study Summary
This is a randomized, blinded, placebo-controlled study of Efimosfermin in obese participants at risk for, or with biopsy-confirmed, nonalcoholic steatohepatitis (NASH), with a single arm open-label extension. It includes Parts A, B, C and D.
Primary Outcome
The effects of Efimosfermin on safety and tolerability will be assessed.
Interventions
- DRUG Placebo
- DRUG Efimosfermin
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 231 participants |
| Start Date | 2021-09-30 |
| Est. Completion | 2025-10-27 |
| Phase | Phase 2 |
What the finished NCT04880031 record still lists
NCT04880031 is an interventional study that assigns participants to a tested intervention. The registered 231 participants enrollment target is mid-sized for trials with a published cap, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (74% higher).
The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.
NCT04880031 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04880031 about?
NCT04880031 is a clinical study titled "A Study of BOS-580 in Obese Subjects at Risk for, or With Biopsy-confirmed, Nonalcoholic Steatohepatitis (NASH) With an Extension". This is a randomized, blinded, placebo-controlled study of Efimosfermin in obese participants at risk for, or with biopsy-confirmed, nonalcoholic steatohepatitis (NASH), with a single arm open-label extension. It includes Parts A, B, C and D.
What is the current status of trial NCT04880031?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 231 participants. The study started on 2021-09-30. Estimated completion is 2025-10-27.
What interventions are being tested in trial NCT04880031?
The interventions under investigation include: Placebo (DRUG), Efimosfermin (DRUG).
Who is sponsoring clinical trial NCT04880031?
This trial is sponsored by GlaxoSmithKline, which has 1,345 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04880031's enrollment target sits among peer trials
231 257th of 2000 higher than 1,744 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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