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NCT04871074 · ClinicalTrials.gov registry record · Phase 2

The Synapse Project

A Phase 2 study, sponsored by University of Wisconsin, Madison.

Completed
Registry status
Phase 2
Development phase
100
Enrollment target

NCT04871074 is a Phase 2 study that has completed, run by University of Wisconsin, Madison. The registered enrollment target is 100 participants.

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The verdict

NCT04871074, a Phase 2 study, has completed, sponsored by University of Wisconsin, Madison.

COMPLETED
Registry status
Phase 2
Development phase
100 participants
Enrollment target

Study Summary

The overarching goal of this project is to use \[C-11\]UCB-J to obtain spatial information on neuronal synapse abundance and inform Alzheimer's disease (AD) progression. The investigators propose to collect longitudinal amyloid, tau, and Synaptic vesicle glycoprotein 2A (SV2A) positron emission tomography (PET) in participants in the Wisconsin Alzheimer's Disease Research Center (ADRC) and Wisconsin Registry for Alzheimer's Prevention (WRAP) across the clinical stages of AD, including cognitively unimpaired biomarker negative, unimpaired biomarker positive, mild cognitive impairment (MCI), and dementia due to AD.

Interventions

  • DEVICE MRI Scan
  • DEVICE PET Scan
  • DRUG UCB-J

Trial Details

FieldValue
Enrollment Target 100 participants
Start Date 2018-11-18
Est. Completion 2025-05-01
Phase Phase 2

Sponsor

University of Wisconsin, Madison

1,039 total trials

What the Registry Record Tells You About NCT04871074

The ClinicalTrials.gov registry entry for NCT04871074 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 100 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Wisconsin, Madison, which has 1,039 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 3 interventions - of which MRI Scan is the first listed.

NCT04871074 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT04871074 about?

NCT04871074 is a clinical study titled "The Synapse Project". The overarching goal of this project is to use \[C-11\]UCB-J to obtain spatial information on neuronal synapse abundance and inform Alzheimer's disease (AD) progression. The investigators propose to collect longitudinal amyloid, tau, and Synaptic vesicle glycoprotein 2A (SV2A) positron emission tomo...

What is the current status of trial NCT04871074?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 100 participants. The study started on 2018-11-18. Estimated completion is 2025-05-01.

What interventions are being tested in trial NCT04871074?

The interventions under investigation include: MRI Scan (DEVICE), PET Scan (DEVICE), UCB-J (DRUG).

Who is sponsoring clinical trial NCT04871074?

This trial is sponsored by University of Wisconsin, Madison, which has 1,039 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.