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NCT04869943 · ClinicalTrials.gov registry record · Phase 3
Efficacy Evaluation of Enobosarm Monotherapy in Treatment of AR+/ER+/HER2- Metastatic Breast Cancer
A Phase 3 study, sponsored by Veru.
- Terminated
- Registry status
- Phase 3
- Development phase
- 52
- Enrollment target
NCT04869943: Clinical Trial Phase 3 study, sponsored by Veru.
NCT04869943 is a Phase 3 study that was terminated before completion, run by Veru. The registered enrollment target is 52 participants, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (93% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04869943, a Phase 3 study, was terminated before completion, sponsored by Veru.
- TERMINATED
- Registry status
- Phase 3
- Development phase
- 52 participants
- Enrollment target
Study Summary
To demonstrate the efficacy of enobosarmin the treatment of androgen receptor positive (AR+) and estrogen receptor positive (ER+) metastatic breast cancer (MBC) as measured by radiographic progression free survival (rPFS).
Primary Outcome
The primary endpoint for the study is the median radiographic progression free survival (rPFS) in the Enobosarm Treatment Group compared to the Control Treatment Group. Progression will be defined based on RECIST 1.1.
Interventions
- DRUG Exemestane
- DRUG Enobosarm
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 52 participants |
| Start Date | 2021-10-12 |
| Est. Completion | 2024-01-09 |
| Phase | Phase 3 |
Why NCT04869943 stopped before completion
NCT04869943 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 52 participants, a relatively small participant target, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (93% lower).
The record links to 0 conditions, and to 2 interventions - of which Exemestane is the first listed.
NCT04869943 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04869943 about?
NCT04869943 is a clinical study titled "Efficacy Evaluation of Enobosarm Monotherapy in Treatment of AR+/ER+/HER2- Metastatic Breast Cancer". To demonstrate the efficacy of enobosarmin the treatment of androgen receptor positive (AR+) and estrogen receptor positive (ER+) metastatic breast cancer (MBC) as measured by radiographic progression free survival (rPFS).
What is the current status of trial NCT04869943?
This trial is currently terminated. It is a Phase 3 study. The enrollment target is 52 participants. The study started on 2021-10-12. Estimated completion is 2024-01-09.
What interventions are being tested in trial NCT04869943?
The interventions under investigation include: Exemestane (DRUG), Enobosarm (DRUG).
Who is sponsoring clinical trial NCT04869943?
This trial is sponsored by Veru, which has 10 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04869943's enrollment target sits among peer trials
52 1841st of 2000 higher than 159 of 2,000 other Phase 3 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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