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NCT04861428 · ClinicalTrials.gov registry record · NA
Heat-not-burn Tobacco Product to Aid in Switching From Combustible to Noncombustible Nicotine (IQOS)
A NA study, sponsored by University of Pittsburgh.
- Terminated
- Registry status
- NA
- Development phase
- 4
- Enrollment target
NCT04861428: Clinical Trial NA study, sponsored by University of Pittsburgh.
NCT04861428 is a NA study that was terminated before completion, run by University of Pittsburgh. The registered enrollment target is 4 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (100% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04861428, a NA study, was terminated before completion, sponsored by University of Pittsburgh.
- TERMINATED
- Registry status
- NA
- Development phase
- 4 participants
- Enrollment target
Study Summary
A novel heat-not-burn tobacco product (IQOS) will be provided to smokers, compared against a (cigarette) smoking as usual period in counter-balanced order in a cross-over design. This study will examine the short-term effects of IQOS, switching from combustible to noncombustible nicotine and withdrawal-related symptoms over a two week-long "practice" period, relative to smoking as usual.
Primary Outcome
Assessed daily using a mobile carbon monoxide monitor (iCO) provided to participants. Carbon monoxide (CO) readings parts per million (ppm) will be submitted directly via email using the iCO smartphone app.
Interventions
- OTHER IQOS
- OTHER Smoking as Usual
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 4 participants |
| Start Date | 2021-06-23 |
| Est. Completion | 2022-04-30 |
| Phase | NA |
Why NCT04861428 stopped before completion
NCT04861428 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 4 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (100% lower).
The record links to 0 conditions, and to 2 interventions - of which IQOS is the first listed.
NCT04861428 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04861428 about?
NCT04861428 is a clinical study titled "Heat-not-burn Tobacco Product to Aid in Switching From Combustible to Noncombustible Nicotine (IQOS)". A novel heat-not-burn tobacco product (IQOS) will be provided to smokers, compared against a (cigarette) smoking as usual period in counter-balanced order in a cross-over design. This study will examine the short-term effects of IQOS, switching from combustible to noncombustible nicotine and withdra...
What is the current status of trial NCT04861428?
This trial is currently terminated. It is a NA study. The enrollment target is 4 participants. The study started on 2021-06-23. Estimated completion is 2022-04-30.
What interventions are being tested in trial NCT04861428?
The interventions under investigation include: IQOS (OTHER), Smoking as Usual (OTHER).
Who is sponsoring clinical trial NCT04861428?
This trial is sponsored by University of Pittsburgh, which has 1,238 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04861428's enrollment target sits among peer trials
4 1996th of 2000 higher than 5 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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