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NCT04858178 · ClinicalTrials.gov registry record · NA

Transcutaneous Spinal Cord Neuromodulation to Normalize Autonomic Phenotypes

A NA study, sponsored by Spaulding Rehabilitation Hospital.

Completed
Registry status
NA
Development phase
4
Enrollment target

NCT04858178 is a NA study that has completed, run by Spaulding Rehabilitation Hospital. The registered enrollment target is 4 participants.

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The verdict

NCT04858178, a NA study, has completed, sponsored by Spaulding Rehabilitation Hospital.

COMPLETED
Registry status
NA
Development phase
4 participants
Enrollment target

Study Summary

This study looks to characterize autonomic nervous system dysfunction after spinal cord injury and identify the potential role that transcutaneous spinal cord stimulation may play at altering neuroregulation. The autonomic nervous system plays key parts in regulation of blood pressure, skin blood flow, and bladder health- all issues that individuals with spinal cord injury typically encounter complications. For both individuals with spinal cord injury and uninjured controls, experiments will utilize multiple parallel recordings to identify how the autonomic nervous system is able to inhibit and activate sympathetic signals. The investigators anticipate that those with autonomic dysfunction after spinal cord injury will exhibit abnormalities in these precise metrics. In both study populations, transcutaneous spinal cord stimulation will be added, testing previously advocated parameters to alter autonomic neuroregulation. In accomplishing this, the investigators hope to give important insights to how the autonomic nervous system works after spinal cord injury and if it's function can be improved utilizing neuromodulation.

Interventions

  • DIAGNOSTIC_TEST Tests of sympathetic inhibition
  • DIAGNOSTIC_TEST Tests of sympathetic activation
  • DIAGNOSTIC_TEST Testing of autonomic dysreflexia
  • DEVICE Transcutaneous spinal cord stimulation

Trial Details

FieldValue
Enrollment Target 4 participants
Start Date 2022-02-17
Est. Completion 2022-11-14
Phase NA

Sponsor

Spaulding Rehabilitation Hospital

101 total trials

What the Registry Record Tells You About NCT04858178

The ClinicalTrials.gov registry entry for NCT04858178 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 4 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Spaulding Rehabilitation Hospital, which has 101 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 4 interventions - of which Tests of sympathetic inhibition is the first listed.

NCT04858178 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT04858178 about?

NCT04858178 is a clinical study titled "Transcutaneous Spinal Cord Neuromodulation to Normalize Autonomic Phenotypes". This study looks to characterize autonomic nervous system dysfunction after spinal cord injury and identify the potential role that transcutaneous spinal cord stimulation may play at altering neuroregulation. The autonomic nervous system plays key parts in regulation of blood pressure, skin blood fl...

What is the current status of trial NCT04858178?

This trial is currently completed. It is a NA study. The enrollment target is 4 participants. The study started on 2022-02-17. Estimated completion is 2022-11-14.

What interventions are being tested in trial NCT04858178?

The interventions under investigation include: Tests of sympathetic inhibition (DIAGNOSTIC_TEST), Tests of sympathetic activation (DIAGNOSTIC_TEST), Testing of autonomic dysreflexia (DIAGNOSTIC_TEST), Transcutaneous spinal cord stimulation (DEVICE).

Who is sponsoring clinical trial NCT04858178?

This trial is sponsored by Spaulding Rehabilitation Hospital, which has 101 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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