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NCT04854122 · ClinicalTrials.gov registry record · NA
Blood Flow Regulation in Individuals With Down Syndrome - Training Study
A NA study, sponsored by University of Nevada, Las Vegas.
- Completed
- Registry status
- NA
- Development phase
- 60
- Enrollment target
NCT04854122: Completed NA study, sponsored by University of Nevada, Las Vegas.
NCT04854122 is a NA study that has completed, run by University of Nevada, Las Vegas. The registered enrollment target is 60 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (96% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04854122, a NA study, has completed, sponsored by University of Nevada, Las Vegas.
- COMPLETED
- Registry status
- NA
- Development phase
- 60 participants
- Enrollment target
Study Summary
Work capacity is an important predictor of declining health or physical function, and of mortality, and is commonly measured as peak oxygen consumption. Peak oxygen consumption is very low in individuals with Down syndrome, the most prevalent genetic cause of intellectual disability. Previous research suggests individuals with Down syndrome may experience a double disadvantage when they are exercising: they may not be able to increase cardiac output sufficiently and they may not be able to allocate adequate blood flow to the working muscles. The aim of this research proposal is therefore to investigate the responses in central and peripheral blood flow regulation and cardiac autonomic function to exercise training in individuals with DS. Additionally the effects of exercise on gait, balance and attitude towards exercise in individuals with DS are investigated.
Primary Outcome
Change in work capacity from baseline to 13 weeks, as measured by peak oxygen uptake in ml/kg/min with a graded exercise test on a treadmill.
Interventions
- BEHAVIORAL Combined exercise intervention
- BEHAVIORAL Usual care / Sham intervention
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 60 participants |
| Start Date | 2021-09-09 |
| Est. Completion | 2024-08-31 |
| Phase | NA |
What the finished NCT04854122 record still lists
NCT04854122 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 60 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (96% lower).
The record links to 0 conditions, and to 2 interventions - of which Combined exercise intervention is the first listed.
NCT04854122 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04854122 about?
NCT04854122 is a clinical study titled "Blood Flow Regulation in Individuals With Down Syndrome - Training Study". Work capacity is an important predictor of declining health or physical function, and of mortality, and is commonly measured as peak oxygen consumption. Peak oxygen consumption is very low in individuals with Down syndrome, the most prevalent genetic cause of intellectual disability. Previous resear...
What is the current status of trial NCT04854122?
This trial is currently completed. It is a NA study. The enrollment target is 60 participants. The study started on 2021-09-09. Estimated completion is 2024-08-31.
What interventions are being tested in trial NCT04854122?
The interventions under investigation include: Combined exercise intervention (BEHAVIORAL), Usual care / Sham intervention (BEHAVIORAL).
Who is sponsoring clinical trial NCT04854122?
This trial is sponsored by University of Nevada, Las Vegas, which has 52 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04854122's enrollment target sits among peer trials
60 1164th of 2000 higher than 745 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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