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NCT04850313 · ClinicalTrials.gov registry record · NA
Evaluating the Use of ProKera Plus® in the Management of Bacterial Corneal Ulcers
A NA study, sponsored by University of Arkansas.
- Terminated
- Registry status
- NA
- Development phase
- 3
- Enrollment target
NCT04850313: Clinical Trial NA study, sponsored by University of Arkansas.
NCT04850313 is a NA study that was terminated before completion, run by University of Arkansas. The registered enrollment target is 3 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (100% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04850313, a NA study, was terminated before completion, sponsored by University of Arkansas.
- TERMINATED
- Registry status
- NA
- Development phase
- 3 participants
- Enrollment target
Study Summary
The study design is a prospective, randomized, controlled interventional study to compare the outcome of ProKera Plus® with conventional treatment in patients with vision-threatening bacterial corneal ulcers. The study will be conducted at the University of Arkansas Medical Sciences (UAMS) in two phases for patients who present to an Ophthalmology clinic or Emergency Department at UAMS.
Primary Outcome
Visual acuity (VA) was assessed for participants applicable study eye using a Snellen letter chart. VA was collected in Snellen and converted to logarithm minimum angle of resolution (logMAR). A logMAR value of 0 equates to 20/20 Snellen visual acuity (normal distance eyesight), with lower logMAR values indicating better visual acuity.
Interventions
- DEVICE ProProKera Plus®
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 3 participants |
| Start Date | 2021-11-09 |
| Est. Completion | 2022-09-30 |
| Phase | NA |
Why NCT04850313 stopped before completion
NCT04850313 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 3 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (100% lower).
The record links to 0 conditions, and to 1 intervention - of which ProProKera Plus® is the first listed.
NCT04850313 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04850313 about?
NCT04850313 is a clinical study titled "Evaluating the Use of ProKera Plus® in the Management of Bacterial Corneal Ulcers". The study design is a prospective, randomized, controlled interventional study to compare the outcome of ProKera Plus® with conventional treatment in patients with vision-threatening bacterial corneal ulcers. The study will be conducted at the University of Arkansas Medical Sciences (UAMS) in two ph...
What is the current status of trial NCT04850313?
This trial is currently terminated. It is a NA study. The enrollment target is 3 participants. The study started on 2021-11-09. Estimated completion is 2022-09-30.
What interventions are being tested in trial NCT04850313?
The interventions under investigation include: ProProKera Plus® (DEVICE).
Who is sponsoring clinical trial NCT04850313?
This trial is sponsored by University of Arkansas, which has 318 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04850313's enrollment target sits among peer trials
3 1996th of 2000 higher than 4 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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