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NCT04836923 · ClinicalTrials.gov registry record · NA
LIFT Intervention in Liver Transplant Candidates
A NA study, sponsored by Northwestern University.
- Completed
- Registry status
- NA
- Development phase
- 81
- Enrollment target
NCT04836923: Completed NA study, sponsored by Northwestern University.
NCT04836923 is a NA study that has completed, run by Northwestern University. The registered enrollment target is 81 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (94% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04836923, a NA study, has completed, sponsored by Northwestern University.
- COMPLETED
- Registry status
- NA
- Development phase
- 81 participants
- Enrollment target
Study Summary
Frailty is a significant problem in patients undergoing liver transplant and is associated with poor outcomes and survival. Hence, optimizing physical fitness and counteracting frailty is important. However, many interventions are very resource intensive and therefore not feasible. In this study, the investigators aim to test the effectiveness of a newly designed intervention to improve frailty in liver transplant candidates. The "LIver FrailTy" intervention (LIFT) will consist of an evaluation by a physical therapist, an individualized home exercise prescription (HEP), exercise tracking using a smart phone application, daily text reminders to exercise and recurrent telephone check-ins.
Primary Outcome
Frailty is described as a biologic syndrome of decreased physiologic reserve and increased vulnerability to health stressors. This outcome is measured by the Liver frailty index \[LFI\]. LFI is composed of 3 performance-based tests (grip strength, chair stands, and balance). Patients are classified using established cutoffs (frail: LFI ≥ 4.5, pre-frail: LFI 3.3-4.4, robust: LFI ≤ 3.2). Higher LFI scores indicate a higher degree of frailty.
Interventions
- BEHAVIORAL "LIver FrailTy" intervention (LIFT)
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 81 participants |
| Start Date | 2020-10-01 |
| Est. Completion | 2024-03-01 |
| Phase | NA |
What the finished NCT04836923 record still lists
NCT04836923 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 81 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (94% lower).
The record links to 0 conditions, and to 1 intervention - of which "LIver FrailTy" intervention (LIFT) is the first listed.
NCT04836923 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04836923 about?
NCT04836923 is a clinical study titled "LIFT Intervention in Liver Transplant Candidates". Frailty is a significant problem in patients undergoing liver transplant and is associated with poor outcomes and survival. Hence, optimizing physical fitness and counteracting frailty is important. However, many interventions are very resource intensive and therefore not feasible. In this study, t...
What is the current status of trial NCT04836923?
This trial is currently completed. It is a NA study. The enrollment target is 81 participants. The study started on 2020-10-01. Estimated completion is 2024-03-01.
What interventions are being tested in trial NCT04836923?
The interventions under investigation include: "LIver FrailTy" intervention (LIFT) (BEHAVIORAL).
Who is sponsoring clinical trial NCT04836923?
This trial is sponsored by Northwestern University, which has 1,209 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04836923's enrollment target sits among peer trials
81 992nd of 2000 higher than 1,007 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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