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NCT04830163 · ClinicalTrials.gov registry record · Phase 1
Brain State-dependent PCMS in Chronic Stroke
A Phase 1 study, sponsored by University of Texas at Austin.
- Not yet
- Registry status
- Phase 1
- Development phase
- 45
- Enrollment target
NCT04830163: Clinical Trial Phase 1 study, sponsored by University of Texas at Austin.
NCT04830163 is a Phase 1 study that has not yet begun recruiting, run by University of Texas at Austin. The registered enrollment target is 45 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (25% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04830163, a Phase 1 study, has not yet begun recruiting, sponsored by University of Texas at Austin.
- NOT YET RECRUITING
- Registry status
- Phase 1
- Development phase
- 45 participants
- Enrollment target
Study Summary
After stroke, people often have difficulty using their hands. Combined brain and nerve stimulation can strengthen the neural pathways that control hand function. In this study, we will deliver combined brain and nerve stimulation during specific time windows that increase activation of neural pathways underlying hand function. We will compare the effects of combined brain and nerve stimulation during these optimal time windows to the effects of combined brain and nerve stimulation applied during random time windows on post-stroke hand function.
Primary Outcome
This will be measured using maximum voluntary contractions of the stroke-affected first dorsal interosseous hand muscle during pinching actions.
Interventions
- COMBINATION_PRODUCT Brain state-dependent paired corticomotoneuronal stimulation (PCMS)
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 45 participants |
| Start Date | 2026-01-01 |
| Est. Completion | 2031-07 |
| Phase | Phase 1 |
What is known before NCT04830163 opens enrollment
NCT04830163 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 45 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (25% lower).
The record links to 0 conditions, and to 1 intervention - of which Brain state-dependent paired corticomotoneuronal stimulation (PCMS) is the first listed.
NCT04830163 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04830163 about?
NCT04830163 is a clinical study titled "Brain State-dependent PCMS in Chronic Stroke". After stroke, people often have difficulty using their hands. Combined brain and nerve stimulation can strengthen the neural pathways that control hand function. In this study, we will deliver combined brain and nerve stimulation during specific time windows that increase activation of neural pathwa...
What is the current status of trial NCT04830163?
This trial is currently not yet recruiting. It is a Phase 1 study. The enrollment target is 45 participants. The study started on 2026-01-01. Estimated completion is 2031-07.
What interventions are being tested in trial NCT04830163?
The interventions under investigation include: Brain state-dependent paired corticomotoneuronal stimulation (PCMS) (COMBINATION_PRODUCT).
Who is sponsoring clinical trial NCT04830163?
This trial is sponsored by University of Texas at Austin, which has 257 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04830163's enrollment target sits among peer trials
45 1066th of 2000 higher than 915 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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