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NCT04825275 · ClinicalTrials.gov registry record · Early Phase 1
Neuro-pharmacological Properties of Repurposed Posaconazole in Glioblastoma: A Phase 0 Clinical Trial
A Early Phase 1 study, sponsored by Milton S. Hershey Medical Center.
- Terminated
- Registry status
- Early Phase 1
- Development phase
- 7
- Enrollment target
NCT04825275: Clinical Trial Early Phase 1 study, sponsored by Milton S. Hershey Medical Center.
NCT04825275 is a Early Phase 1 study that was terminated before completion, run by Milton S. Hershey Medical Center. The registered enrollment target is 7 participants, below the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (87% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04825275, a Early Phase 1 study, was terminated before completion, sponsored by Milton S. Hershey Medical Center.
- TERMINATED
- Registry status
- Early Phase 1
- Development phase
- 7 participants
- Enrollment target
Study Summary
This research is being done to find out if the study drug (posaconazole) can enter brain tumors at a high enough amount to stop the tumor cells from dividing. Posaconazole is a drug which doctors already use for fungal infections and is thought to be able to effect tumor cells. As treatments for this type of brain tumor are limited, it is hoped that the results of this study will help to determine if the study drug should be studied further as a possible treatment.
Primary Outcome
Assessment of the concentration of drug in the dialysate fluid.
Interventions
- DRUG Posaconazole Pill
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 7 participants |
| Start Date | 2022-05-13 |
| Est. Completion | 2024-11-06 |
| Phase | Early Phase 1 |
Why NCT04825275 stopped before completion
NCT04825275 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 7 participants, a relatively small participant target, below the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (87% lower).
The record links to 0 conditions, and to 1 intervention - of which Posaconazole Pill is the first listed.
NCT04825275 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04825275 about?
NCT04825275 is a clinical study titled "Neuro-pharmacological Properties of Repurposed Posaconazole in Glioblastoma: A Phase 0 Clinical Trial". This research is being done to find out if the study drug (posaconazole) can enter brain tumors at a high enough amount to stop the tumor cells from dividing. Posaconazole is a drug which doctors already use for fungal infections and is thought to be able to effect tumor cells. As treatments for thi...
What is the current status of trial NCT04825275?
This trial is currently terminated. It is a Early Phase 1 study. The enrollment target is 7 participants. The study started on 2022-05-13. Estimated completion is 2024-11-06.
What interventions are being tested in trial NCT04825275?
The interventions under investigation include: Posaconazole Pill (DRUG).
Who is sponsoring clinical trial NCT04825275?
This trial is sponsored by Milton S. Hershey Medical Center, which has 396 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04825275's enrollment target sits among peer trials
7 1825th of 2000 higher than 156 of 2,000 other Early Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Early Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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