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NCT04821557 · ClinicalTrials.gov registry record · NA
Effect of Microbial Protease Supplementation on Postprandial Amino Acid Levels
A NA study, sponsored by University of Illinois at Urbana-Champaign.
- Completed
- Registry status
- NA
- Development phase
- 24
- Enrollment target
NCT04821557 is a NA study that has completed, run by University of Illinois at Urbana-Champaign. The registered enrollment target is 24 participants.
The verdict
NCT04821557, a NA study, has completed, sponsored by University of Illinois at Urbana-Champaign.
- COMPLETED
- Registry status
- NA
- Development phase
- 24 participants
- Enrollment target
Study Summary
Dietary protein is digested in the stomach and intestines to smaller peptides and 20 individual amino acids which, when absorbed by the gut into circulation and taken up by skeletal muscle, help stimulate muscle protein synthesis (MPS). Amino acids also provide the building blocks for muscle proteins that contribute to lean mass gains and increased strength following resistance exercise. Therefore, strategies to efficiently maximize amino acid exposure without overconsumption are warranted. Oral enzyme supplementation is a candidate approach to optimize amino acid absorption from dietary protein and protein supplements. Microbial proteases, approved for dietary supplement use, can theoretically speed up the conversion of protein and peptides to amino acids. Protease supplements have been marketed to promote muscle strength by optimizing amino acid absorption, however the clinical evidence is limited. This work will support that ingestion of protease supplements with a meal can allow individuals to more efficiently increase amino acid levels from a given amount of dietary protein.
Interventions
- DIETARY_SUPPLEMENT Protease + Protein
- DIETARY_SUPPLEMENT Placebo + Protein
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 24 participants |
| Start Date | 2021-03-30 |
| Est. Completion | 2021-09-03 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT04821557
The ClinicalTrials.gov registry entry for NCT04821557 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 24 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Illinois at Urbana-Champaign, which has 129 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 2 interventions - of which Protease + Protein is the first listed.
NCT04821557 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT04821557 about?
NCT04821557 is a clinical study titled "Effect of Microbial Protease Supplementation on Postprandial Amino Acid Levels". Dietary protein is digested in the stomach and intestines to smaller peptides and 20 individual amino acids which, when absorbed by the gut into circulation and taken up by skeletal muscle, help stimulate muscle protein synthesis (MPS). Amino acids also provide the building blocks for muscle protein...
What is the current status of trial NCT04821557?
This trial is currently completed. It is a NA study. The enrollment target is 24 participants. The study started on 2021-03-30. Estimated completion is 2021-09-03.
What interventions are being tested in trial NCT04821557?
The interventions under investigation include: Protease + Protein (DIETARY_SUPPLEMENT), Placebo + Protein (DIETARY_SUPPLEMENT).
Who is sponsoring clinical trial NCT04821557?
This trial is sponsored by University of Illinois at Urbana-Champaign, which has 129 total clinical trials registered on ClinicalTrials.gov.
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