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NCT04806282 · ClinicalTrials.gov registry record
Deep Phenotyping of Hearing Instability Disorders: Cohort Establishment, Biomarker Identification, Development of Novel Phenotyping Measures, and Discovery of Therapeutic Targets
A clinical trial, sponsored by National Institute on Deafness and Other Communication Disorders (NIDCD).
- Recruiting
- Registry status
- 210
- Enrollment target
NCT04806282: Recruiting study, sponsored by National Institute on Deafness and Other Communication Disorders (NIDCD).
NCT04806282 is a clinical trial that is actively recruiting participants, run by National Institute on Deafness and Other Communication Disorders (NIDCD). The registered enrollment target is 210 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04806282 is actively recruiting participants, sponsored by National Institute on Deafness and Other Communication Disorders (NIDCD).
- RECRUITING
- Registry status
- 210 participants
- Enrollment target
Study Summary
Background: Disorders of hearing instability (HI) are poorly characterized and ineffectively treated. HI can cause fluctuations in hearing thresholds and speech understanding. Researchers want to use a specialized form of magnetic resonance imaging (MRI) and blood tests to learn more about HI. Objective: To characterize a cohort of people with HI and to correlate HI with other data, including hearing evaluations, as well as radiologic and immunologic biomarkers of inflammation over time. Eligibility: Adults ages 18-80 who have symptoms consistent with possible HI. Design: Participants will be screened with a medical and hearing history and medical record review. Participants will have physical exams. Their head and neck will be examined. They will have blood drawn. Participants will have hearing tests. They will wear headphones or foam earplugs. They will listen to different tones. They may describe what they hear. Participants will have balance tests. They will wear goggles as they watch moving lights or while cold or warm air is blown into their ears. They will sit in a spinning chair in a quiet, dark booth. From a reclining position, they will raise their head while clicking sounds are played into their ears. Participants will have MRIs of the inner ear and brain. The MRI scanner is a metal cylinder surrounded by a strong magnetic field. During the MRIs, participants will lie on a table that slides in and out of the scanner. Soft padding or a coil will be placed around their head. They will get a contrast agent through an intravenous catheter. Participation will last up to 15 months. ...
Primary Outcome
To identify phenotype features associated with hearing fluctuation
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 210 participants |
| Start Date | 2021-08-17 |
| Est. Completion | 2030-12-31 |
What NCT04806282 shows while recruiting
NCT04806282 is an observational study that tracks outcomes without assigning an intervention. The registered 210 participants enrollment target is mid-sized for trials with a published cap.
The record links to 0 conditions, and to 0 interventions.
NCT04806282 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04806282 about?
NCT04806282 is a clinical study titled "Deep Phenotyping of Hearing Instability Disorders: Cohort Establishment, Biomarker Identification, Development of Novel Phenotyping Measures, and Discovery of Therapeutic Targets". Background: Disorders of hearing instability (HI) are poorly characterized and ineffectively treated. HI can cause fluctuations in hearing thresholds and speech understanding. Researchers want to use a specialized form of magnetic resonance imaging (MRI) and blood tests to learn more about HI. Obj...
What is the current status of trial NCT04806282?
This trial is currently recruiting. The enrollment target is 210 participants. The study started on 2021-08-17. Estimated completion is 2030-12-31.
Who is sponsoring clinical trial NCT04806282?
This trial is sponsored by National Institute on Deafness and Other Communication Disorders (NIDCD), which has 34 total clinical trials registered on ClinicalTrials.gov.
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