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NCT04801043 · ClinicalTrials.gov registry record · Phase 1

To Evaluate the Pharmacokinetics of XNW4107 in Healthy Adult Young Females and in Healthy Adult Elderly Males and Females.

A Phase 1 study, sponsored by Evopoint Biosciences.

Completed
Registry status
Phase 1
Development phase
24
Enrollment target

NCT04801043: Completed Phase 1 study, sponsored by Evopoint Biosciences.

NCT04801043 is a Phase 1 study that has completed, run by Evopoint Biosciences. The registered enrollment target is 24 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (60% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT04801043, a Phase 1 study, has completed, sponsored by Evopoint Biosciences.

COMPLETED
Registry status
Phase 1
Development phase
24 participants
Enrollment target

Study Summary

This is a Phase 1, randomized, double-blind, placebo-controlled study to assess the PK, safety and tolerability of XNW4107, imipenem and cilastatin administered by 60-min (± 3 min) IV infusion in healthy adult young females and in healthy adult elderly males and females.

Interventions

  • DRUG placebo
  • DRUG XNW4107
  • DRUG Imipenem/Cilastatin

Trial Details

FieldValue
Enrollment Target 24 participants
Start Date 2021-03-02
Est. Completion 2022-01-31
Phase Phase 1
Evopoint Biosciences

5 total trials

What the finished NCT04801043 record still lists

NCT04801043 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 24 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (60% lower).

The record links to 0 conditions, and to 3 interventions - of which placebo is the first listed.

NCT04801043 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT04801043 about?

NCT04801043 is a clinical study titled "To Evaluate the Pharmacokinetics of XNW4107 in Healthy Adult Young Females and in Healthy Adult Elderly Males and Females.". This is a Phase 1, randomized, double-blind, placebo-controlled study to assess the PK, safety and tolerability of XNW4107, imipenem and cilastatin administered by 60-min (± 3 min) IV infusion in healthy adult young females and in healthy adult elderly males and females.

What is the current status of trial NCT04801043?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 24 participants. The study started on 2021-03-02. Estimated completion is 2022-01-31.

What interventions are being tested in trial NCT04801043?

The interventions under investigation include: placebo (DRUG), XNW4107 (DRUG), Imipenem/Cilastatin (DRUG).

Who is sponsoring clinical trial NCT04801043?

This trial is sponsored by Evopoint Biosciences, which has 5 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT04801043's enrollment target sits among peer trials

24 1520th of 2000 higher than 405 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT04801043, the US trial registry maintained by the National Library of Medicine. NCT04801043 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.