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NCT04799171 · ClinicalTrials.gov registry record · NA
Aging and the Mitochondrial Response to Exercise Training, Measured by Noninvasive 31P Magnetic Resonance Spectroscopy
A NA study, sponsored by Pennington Biomedical Research Center.
- Completed
- Registry status
- NA
- Development phase
- 352
- Enrollment target
NCT04799171: Completed NA study, sponsored by Pennington Biomedical Research Center.
NCT04799171 is a NA study that has completed, run by Pennington Biomedical Research Center. The registered enrollment target is 352 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (75% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04799171, a NA study, has completed, sponsored by Pennington Biomedical Research Center.
- COMPLETED
- Registry status
- NA
- Development phase
- 352 participants
- Enrollment target
Study Summary
The goal of the study is to determine whether aerobic or resistant exercise can improve in vivo mitochondrial capacity of skeletal muscle cells similarly in healthy younger, middle aged and older adults. This confers long-term changes in this tissue which in-turn contribute to improved metabolic health and functional capacity through epigenetic regulation of novel exercise response genes.
Primary Outcome
The plot of PCr peak height vs. time will be fitted with a mono-exponential equation whose free parameters are the recovery time constant (tau) and scaling coefficients. Percent change in tau between pre- and post-intervention scans will be our primary measurement of the maximal mitochondrial capacity response to exercise training.
Interventions
- OTHER Isometric Contraction Exercise - Young Adults (Age group 18-39)
- OTHER Isometric Contraction Exercise - Middle Age Adults (Age group 40-59)
- OTHER Isometric Contraction Exercise - Old Adults (Age group >60)
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 352 participants |
| Start Date | 2021-08-02 |
| Est. Completion | 2025-05-12 |
| Phase | NA |
What the finished NCT04799171 record still lists
NCT04799171 is an interventional study that assigns participants to a tested intervention. The registered 352 participants enrollment target is mid-sized for trials with a published cap, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (75% lower).
The record links to 0 conditions, and to 3 interventions - of which Isometric Contraction Exercise - Young Adults (Age group 18-39) is the first listed.
NCT04799171 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04799171 about?
NCT04799171 is a clinical study titled "Aging and the Mitochondrial Response to Exercise Training, Measured by Noninvasive 31P Magnetic Resonance Spectroscopy". The goal of the study is to determine whether aerobic or resistant exercise can improve in vivo mitochondrial capacity of skeletal muscle cells similarly in healthy younger, middle aged and older adults. This confers long-term changes in this tissue which in-turn contribute to improved metabolic hea...
What is the current status of trial NCT04799171?
This trial is currently completed. It is a NA study. The enrollment target is 352 participants. The study started on 2021-08-02. Estimated completion is 2025-05-12.
What interventions are being tested in trial NCT04799171?
The interventions under investigation include: Isometric Contraction Exercise - Young Adults (Age group 18-39) (OTHER), Isometric Contraction Exercise - Middle Age Adults (Age group 40-59) (OTHER), Isometric Contraction Exercise - Old Adults (Age group >60) (OTHER).
Who is sponsoring clinical trial NCT04799171?
This trial is sponsored by Pennington Biomedical Research Center, which has 258 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04799171's enrollment target sits among peer trials
352 292nd of 2000 higher than 1,709 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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