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NCT04791943 · ClinicalTrials.gov registry record · Phase 2
Preoperative Melatonin to Decrease Analgesia Usage After Third Molar Surgery
A Phase 2 study, sponsored by Montefiore Medical Center.
- Completed
- Registry status
- Phase 2
- Development phase
- 60
- Enrollment target
NCT04791943: Completed Phase 2 study, sponsored by Montefiore Medical Center.
NCT04791943 is a Phase 2 study that has completed, run by Montefiore Medical Center. The registered enrollment target is 60 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (55% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04791943, a Phase 2 study, has completed, sponsored by Montefiore Medical Center.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 60 participants
- Enrollment target
Study Summary
The purpose of the study is to assess if melatonin given for three nights before wisdom tooth surgery decreases post-operative pain and pain medication consumption. Patients will receive either melatonin or a placebo for three nights prior to surgery.
Primary Outcome
Postoperative consumption of narcotic pain medication will be measured for approximately 72 hours post operatively. Three total surveys will be administered. The surveys will be sent to participants via text message or email and include a link to SurveyMonkey. These surveys will be sent in the morning approximately 1 day, 2 days, and 3 days after surgery. The surveys will query for participant identification and then ask how many tablets of ibuprofen 600mg and hydrocodone-acetaminophen have been
Interventions
- DRUG Melatonin 10 MG
- DRUG Lactose pill
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 60 participants |
| Start Date | 2021-11-16 |
| Est. Completion | 2025-10-20 |
| Phase | Phase 2 |
What the finished NCT04791943 record still lists
NCT04791943 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 60 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (55% lower).
The record links to 0 conditions, and to 2 interventions - of which Melatonin 10 MG is the first listed.
NCT04791943 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04791943 about?
NCT04791943 is a clinical study titled "Preoperative Melatonin to Decrease Analgesia Usage After Third Molar Surgery". The purpose of the study is to assess if melatonin given for three nights before wisdom tooth surgery decreases post-operative pain and pain medication consumption. Patients will receive either melatonin or a placebo for three nights prior to surgery.
What is the current status of trial NCT04791943?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 60 participants. The study started on 2021-11-16. Estimated completion is 2025-10-20.
What interventions are being tested in trial NCT04791943?
The interventions under investigation include: Melatonin 10 MG (DRUG), Lactose pill (DRUG).
Who is sponsoring clinical trial NCT04791943?
This trial is sponsored by Montefiore Medical Center, which has 345 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04791943's enrollment target sits among peer trials
60 1027th of 2000 higher than 868 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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