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NCT04789330 · ClinicalTrials.gov registry record · Phase 4
Norepinephrine vs Phenylephrine During General Anesthesia
A Phase 4 study, sponsored by University of California, San Francisco.
- Completed
- Registry status
- Phase 4
- Development phase
- 3,626
- Enrollment target
NCT04789330 is a Phase 4 study that has completed, run by University of California, San Francisco. The registered enrollment target is 3,626 participants.
The verdict
NCT04789330, a Phase 4 study, has completed, sponsored by University of California, San Francisco.
- COMPLETED
- Registry status
- Phase 4
- Development phase
- 3,626 participants
- Enrollment target
Study Summary
50 million patients undergo surgery each year in the United States. Postoperative mortality is considered the third leading cause of death worldwide. Hypotension during surgery have been linked to increased postoperative morbidity and mortality. Episodes of hypotension during surgery are associated with an increased risk of acute kidney injury, stroke, cardiac events and death. Treating or preventing hypotension during general anesthesia and major surgery was found to improve outcomes. At this time, it is unclear what is the best vasopressor to maintain blood pressure during surgery under general anesthesia. With this pilot pragmatic trial, the investigators will explore the impact of norepinephrine (NE) or phenylephrine (PE) on post-operative events in patients undergoing major surgery with general anesthesia and needing vasopressors infusion to maintain their systemic arterial pressure.
Interventions
- DRUG Norepinephrine
- DRUG Phenylephrine
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 3,626 participants |
| Start Date | 2021-07-01 |
| Est. Completion | 2022-04-01 |
| Phase | Phase 4 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT04789330
The ClinicalTrials.gov registry entry for NCT04789330 describes a study currently listed as completed, categorized as Phase 4. The registered enrollment target is 3,626 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of California, San Francisco, which has 1,713 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 2 interventions - of which Norepinephrine is the first listed.
NCT04789330 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT04789330 about?
NCT04789330 is a clinical study titled "Norepinephrine vs Phenylephrine During General Anesthesia". 50 million patients undergo surgery each year in the United States. Postoperative mortality is considered the third leading cause of death worldwide. Hypotension during surgery have been linked to increased postoperative morbidity and mortality. Episodes of hypotension during surgery are associated ...
What is the current status of trial NCT04789330?
This trial is currently completed. It is a Phase 4 study. The enrollment target is 3,626 participants. The study started on 2021-07-01. Estimated completion is 2022-04-01.
What interventions are being tested in trial NCT04789330?
The interventions under investigation include: Norepinephrine (DRUG), Phenylephrine (DRUG).
Who is sponsoring clinical trial NCT04789330?
This trial is sponsored by University of California, San Francisco, which has 1,713 total clinical trials registered on ClinicalTrials.gov.
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