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NCT04786379 · ClinicalTrials.gov registry record · NA

Surgical Management of Knee Septic Arthritis

A NA study, sponsored by Texas Tech University Health Sciences Center, El Paso.

Terminated
Registry status
NA
Development phase
10
Enrollment target

NCT04786379: Clinical Trial NA study, sponsored by Texas Tech University Health Sciences Center, El Paso.

NCT04786379 is a NA study that was terminated before completion, run by Texas Tech University Health Sciences Center, El Paso. The registered enrollment target is 10 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT04786379, a NA study, was terminated before completion, sponsored by Texas Tech University Health Sciences Center, El Paso.

TERMINATED
Registry status
NA
Development phase
10 participants
Enrollment target

Study Summary

Surgical excisional debridement is the mainstay of management in septic arthritis with necessary decompression, lavage, debridement, and partial synovectomy. However, there has been considerable debate over the optimal modality. Most surgeons perform an open arthrotomy or arthroscopic debridement, although serial aspiration can be considered as an option in very limited circumstances with patients who cannot tolerate surgery. While open arthrotomy has been often utilized, there has been an increasing number of proponents for arthroscopic treatment citing lower re-infection rates and better functional outcomes. However, there has been a lack of well-designed prospective studies comparing surgical treatment modalities for native knee septic arthritis. The goals of this present study are to determine if arthroscopic management of septic arthritis in the native knee resulted in a lower number of surgeries and a shorter length of stay compared to open arthrotomy. Secondary outcomes included differences in postoperative pain and improvements in Lysholm knee scores.

Primary Outcome

The total number of surgeries performed during initial admission in order to obtain appropriate clinical response and resultant discharge on outpatient antibiotics.

Interventions

  • PROCEDURE Arthroscopic Irrigation and Debridement
  • PROCEDURE Open Arthrotomy with irrigation and debridement

Trial Details

FieldValue
Enrollment Target 10 participants
Start Date 2021-04-01
Est. Completion 2022-04-30
Phase NA

Why NCT04786379 stopped before completion

NCT04786379 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 10 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower).

The record links to 0 conditions, and to 2 interventions - of which Arthroscopic Irrigation and Debridement is the first listed.

NCT04786379 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT04786379 about?

NCT04786379 is a clinical study titled "Surgical Management of Knee Septic Arthritis". Surgical excisional debridement is the mainstay of management in septic arthritis with necessary decompression, lavage, debridement, and partial synovectomy. However, there has been considerable debate over the optimal modality. Most surgeons perform an open arthrotomy or arthroscopic debridement, a...

What is the current status of trial NCT04786379?

This trial is currently terminated. It is a NA study. The enrollment target is 10 participants. The study started on 2021-04-01. Estimated completion is 2022-04-30.

What interventions are being tested in trial NCT04786379?

The interventions under investigation include: Arthroscopic Irrigation and Debridement (PROCEDURE), Open Arthrotomy with irrigation and debridement (PROCEDURE).

Who is sponsoring clinical trial NCT04786379?

This trial is sponsored by Texas Tech University Health Sciences Center, El Paso, which has 35 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT04786379's enrollment target sits among peer trials

10 1927th of 2000 higher than 26 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT04786379, the US trial registry maintained by the National Library of Medicine. NCT04786379 (small enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.