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NCT04777708 · ClinicalTrials.gov registry record · Early Phase 1

BO-112 and Pembrolizumab for the Treatment of PD-1/PD-L1 Refractory Liver Cancer

A Early Phase 1 study, sponsored by Jonsson Comprehensive Cancer Center.

Terminated
Registry status
Early Phase 1
Development phase
1
Enrollment target

NCT04777708 is a Early Phase 1 study that was terminated before completion, run by Jonsson Comprehensive Cancer Center. The registered enrollment target is 1 participants.

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The verdict

NCT04777708, a Early Phase 1 study, was terminated before completion, sponsored by Jonsson Comprehensive Cancer Center.

TERMINATED
Registry status
Early Phase 1
Development phase
1 participants
Enrollment target

Study Summary

This early phase I trial evaluates the side effects of BO-112 and pembrolizumab and how well they work in treating patients with Barcelona Clinic Liver Cancer (BCLC) stage B or C liver cancer. Immunotherapy with BO-112, may induce changes in body's immune system and may interfere with the ability of tumor cells to grow and spread. Immunotherapy with monoclonal antibodies, such as pembrolizumab, may help the body's immune system attack the tumor, and may interfere with the ability of tumor cells to grow and spread. Giving BO-112 and pembrolizumab may help treat patients with liver cancer.

Interventions

  • BIOLOGICAL Pembrolizumab
  • BIOLOGICAL Nanoplexed Poly I:C BO-112

Trial Details

FieldValue
Enrollment Target 1 participants
Start Date 2021-10-13
Est. Completion 2023-03-13
Phase Early Phase 1

Sponsor

Jonsson Comprehensive Cancer Center

321 total trials

What the Registry Record Tells You About NCT04777708

The ClinicalTrials.gov registry entry for NCT04777708 describes a study currently listed as terminated, categorized as Early Phase 1. The registered enrollment target is 1 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Jonsson Comprehensive Cancer Center, which has 321 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 2 interventions - of which Pembrolizumab is the first listed.

NCT04777708 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT04777708 about?

NCT04777708 is a clinical study titled "BO-112 and Pembrolizumab for the Treatment of PD-1/PD-L1 Refractory Liver Cancer". This early phase I trial evaluates the side effects of BO-112 and pembrolizumab and how well they work in treating patients with Barcelona Clinic Liver Cancer (BCLC) stage B or C liver cancer. Immunotherapy with BO-112, may induce changes in body's immune system and may interfere with the ability of...

What is the current status of trial NCT04777708?

This trial is currently terminated. It is a Early Phase 1 study. The enrollment target is 1 participants. The study started on 2021-10-13. Estimated completion is 2023-03-13.

What interventions are being tested in trial NCT04777708?

The interventions under investigation include: Pembrolizumab (BIOLOGICAL), Nanoplexed Poly I:C BO-112 (BIOLOGICAL).

Who is sponsoring clinical trial NCT04777708?

This trial is sponsored by Jonsson Comprehensive Cancer Center, which has 321 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.