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NCT04776239 · ClinicalTrials.gov registry record · Phase 1
Allogeneic Mesenchymal Human Stem Cell Infusion Therapy for Endothelial DySfunctiOn in Diabetic Subjects With Symptomatic Ischemic Heart Disease. (ACESO-IHD)
A Phase 1 study, sponsored by Joshua M Hare.
- Completed
- Registry status
- Phase 1
- Development phase
- 26
- Enrollment target
NCT04776239: Completed Phase 1 study, sponsored by Joshua M Hare.
NCT04776239 is a Phase 1 study that has completed, run by Joshua M Hare. The registered enrollment target is 26 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (57% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04776239, a Phase 1 study, has completed, sponsored by Joshua M Hare.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 26 participants
- Enrollment target
Study Summary
The purpose of this study is to test the hypothesis that allogeneic Mesenchymal Stem Cells (MSCs) promote systemic and coronary endothelial repair through rescue of bone marrow progenitors in type 2 diabetic patients with symptomatic IHD compared to placebo.
Primary Outcome
FMD% is measured via brachial artery ultrasound. The unit of measure is percent.
Interventions
- OTHER Placebo
- DRUG 100 million Allogeneic Mesenchymal Human Stem Cells
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 26 participants |
| Start Date | 2021-08-16 |
| Est. Completion | 2025-08-26 |
| Phase | Phase 1 |
What the finished NCT04776239 record still lists
NCT04776239 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 26 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (57% lower).
The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.
NCT04776239 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04776239 about?
NCT04776239 is a clinical study titled "Allogeneic Mesenchymal Human Stem Cell Infusion Therapy for Endothelial DySfunctiOn in Diabetic Subjects With Symptomatic Ischemic Heart Disease. (ACESO-IHD)". The purpose of this study is to test the hypothesis that allogeneic Mesenchymal Stem Cells (MSCs) promote systemic and coronary endothelial repair through rescue of bone marrow progenitors in type 2 diabetic patients with symptomatic IHD compared to placebo.
What is the current status of trial NCT04776239?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 26 participants. The study started on 2021-08-16. Estimated completion is 2025-08-26.
What interventions are being tested in trial NCT04776239?
The interventions under investigation include: Placebo (OTHER), 100 million Allogeneic Mesenchymal Human Stem Cells (DRUG).
Who is sponsoring clinical trial NCT04776239?
This trial is sponsored by Joshua M Hare, which has 10 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04776239's enrollment target sits among peer trials
26 1482nd of 2000 higher than 506 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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