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NCT04770493 · ClinicalTrials.gov registry record · Phase 2
Enhancing the Effects of Alcohol Treatment With Lamotrigine
A Phase 2 study, sponsored by Brown University.
- Completed
- Registry status
- Phase 2
- Development phase
- 44
- Enrollment target
NCT04770493: Completed Phase 2 study, sponsored by Brown University.
NCT04770493 is a Phase 2 study that has completed, run by Brown University. The registered enrollment target is 44 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (67% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04770493, a Phase 2 study, has completed, sponsored by Brown University.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 44 participants
- Enrollment target
Study Summary
This study will help determine the tolerability and efficacy of the mood-stabilizing anticonvulsant lamotrigine in youth with alcohol use disorder. It will also help establish whether and how lamotrigine improves outcomes related to alcohol use. The results of this proof-of-concept study will inform whether a future larger clinical trial is warranted.
Primary Outcome
The number and percentage of youth who complete the active medication phase will determine feasibility.
Interventions
- DRUG Placebo
- DRUG Lamotrigine
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 44 participants |
| Start Date | 2022-01-24 |
| Est. Completion | 2024-10-24 |
| Phase | Phase 2 |
What the finished NCT04770493 record still lists
NCT04770493 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 44 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (67% lower).
The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.
NCT04770493 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04770493 about?
NCT04770493 is a clinical study titled "Enhancing the Effects of Alcohol Treatment With Lamotrigine". This study will help determine the tolerability and efficacy of the mood-stabilizing anticonvulsant lamotrigine in youth with alcohol use disorder. It will also help establish whether and how lamotrigine improves outcomes related to alcohol use. The results of this proof-of-concept study will inform...
What is the current status of trial NCT04770493?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 44 participants. The study started on 2022-01-24. Estimated completion is 2024-10-24.
What interventions are being tested in trial NCT04770493?
The interventions under investigation include: Placebo (DRUG), Lamotrigine (DRUG).
Who is sponsoring clinical trial NCT04770493?
This trial is sponsored by Brown University, which has 231 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04770493's enrollment target sits among peer trials
44 1322nd of 2000 higher than 669 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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