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NCT04764396 · ClinicalTrials.gov registry record · NA
Assessing Effects of Heparin Priming and Pass Number on Tissue Quality of Fine Needle Biopsies
A NA study, sponsored by University of Michigan.
- Terminated
- Registry status
- NA
- Development phase
- 2
- Enrollment target
NCT04764396: Clinical Trial NA study, sponsored by University of Michigan.
NCT04764396 is a NA study that was terminated before completion, run by University of Michigan. The registered enrollment target is 2 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (100% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04764396, a NA study, was terminated before completion, sponsored by University of Michigan.
- TERMINATED
- Registry status
- NA
- Development phase
- 2 participants
- Enrollment target
Study Summary
This is a randomized study that will enroll patients scheduled for an endoscopic ultrasound biopsy of a pancreas lesion to be in the heparin or saline group during the procedure. The purpose of this study is to examine the effect of blood contamination, heparin priming of the fine needle biopsies, and pass number on tumor tissue quality in fine needle biopsies. The hypothesis for this study is that fine needle biopsy tissue quality of pancreatic masses decreases with increasing pass number due to blood contamination; this blood contamination can be ameliorated with priming of the needle with an anticoagulant such as heparin.
Primary Outcome
Hematoxylin and eosin (H\&E) slides from the passes 1, 2, and 3 will be compared. The number of cells present on each H\&E slide will be quantified by using image processing software. This value will be total number of cells divided by the total area of the biopsy.
Interventions
- DRUG Saline
- COMBINATION_PRODUCT Heparin will be used for needle priming (BD PosiFlush™ Pre-Filled Heparin Lock Flush Syringe)
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 2 participants |
| Start Date | 2021-03-12 |
| Est. Completion | 2021-07-06 |
| Phase | NA |
Why NCT04764396 stopped before completion
NCT04764396 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 2 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (100% lower).
The record links to 0 conditions, and to 2 interventions - of which Saline is the first listed.
NCT04764396 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04764396 about?
NCT04764396 is a clinical study titled "Assessing Effects of Heparin Priming and Pass Number on Tissue Quality of Fine Needle Biopsies". This is a randomized study that will enroll patients scheduled for an endoscopic ultrasound biopsy of a pancreas lesion to be in the heparin or saline group during the procedure. The purpose of this study is to examine the effect of blood contamination, heparin priming of the fine needle biopsies, ...
What is the current status of trial NCT04764396?
This trial is currently terminated. It is a NA study. The enrollment target is 2 participants. The study started on 2021-03-12. Estimated completion is 2021-07-06.
What interventions are being tested in trial NCT04764396?
The interventions under investigation include: Saline (DRUG), Heparin will be used for needle priming (BD PosiFlush™ Pre-Filled Heparin Lock Flush Syringe) (COMBINATION_PRODUCT).
Who is sponsoring clinical trial NCT04764396?
This trial is sponsored by University of Michigan, which has 1,327 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04764396's enrollment target sits among peer trials
2 1997th of 2000 the lowest of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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