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NCT04759872 · ClinicalTrials.gov registry record · NA
Insulin and Muscle Fat Metabolism
A NA study, sponsored by Oregon State University.
- Terminated
- Registry status
- NA
- Development phase
- 9
- Enrollment target
NCT04759872: Clinical Trial NA study, sponsored by Oregon State University.
NCT04759872 is a NA study that was terminated before completion, run by Oregon State University. The registered enrollment target is 9 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04759872, a NA study, was terminated before completion, sponsored by Oregon State University.
- TERMINATED
- Registry status
- NA
- Development phase
- 9 participants
- Enrollment target
Study Summary
Our objective in this study is to identify the extent to which insulin drives the accumulation of lipids in skeletal muscle of humans. We will test the hypothesis that 4-hours of mild hyperinsulinemia will result in significant muscle lipid accumulation and that such effects will be similar in lean and overweight/obese humans.
Primary Outcome
Liquid chromatography tandem mass spectrometry (targeted lipidomics) will be used to assess species-level changes in skeletal muscle lipid content in biopsy samples collected before and after the insulin infusion to induce mild hyperinsulinemia.
Interventions
- OTHER Hyperinsulinemic-euglycemic Clamp
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 9 participants |
| Start Date | 2021-02-22 |
| Est. Completion | 2022-06-07 |
| Phase | NA |
Why NCT04759872 stopped before completion
NCT04759872 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 9 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower).
The record links to 0 conditions, and to 1 intervention - of which Hyperinsulinemic-euglycemic Clamp is the first listed.
NCT04759872 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04759872 about?
NCT04759872 is a clinical study titled "Insulin and Muscle Fat Metabolism". Our objective in this study is to identify the extent to which insulin drives the accumulation of lipids in skeletal muscle of humans. We will test the hypothesis that 4-hours of mild hyperinsulinemia will result in significant muscle lipid accumulation and that such effects will be similar in lean ...
What is the current status of trial NCT04759872?
This trial is currently terminated. It is a NA study. The enrollment target is 9 participants. The study started on 2021-02-22. Estimated completion is 2022-06-07.
What interventions are being tested in trial NCT04759872?
The interventions under investigation include: Hyperinsulinemic-euglycemic Clamp (OTHER).
Who is sponsoring clinical trial NCT04759872?
This trial is sponsored by Oregon State University, which has 33 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04759872's enrollment target sits among peer trials
9 1975th of 2000 higher than 25 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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