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NCT04757584 · ClinicalTrials.gov registry record · Phase 4
Pilot Deprescribing N-of-1 Trials for Beta-blockers in HFpEF
A Phase 4 study, sponsored by Weill Medical College of Cornell University.
- Completed
- Registry status
- Phase 4
- Development phase
- 9
- Enrollment target
NCT04757584: Completed Phase 4 study, sponsored by Weill Medical College of Cornell University.
NCT04757584 is a Phase 4 study that has completed, run by Weill Medical College of Cornell University. The registered enrollment target is 9 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (98% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04757584, a Phase 4 study, has completed, sponsored by Weill Medical College of Cornell University.
- COMPLETED
- Registry status
- Phase 4
- Development phase
- 9 participants
- Enrollment target
Study Summary
In this study, we will test the feasibility of N-of-1 trials for deprescribing beta-blockers in patients with Heart Failure with Preserved Ejection Fraction. To achieve this objective we will conduct 16 4-period N-of-1 trials (on vs. off) and subsequently interview participants to better understand feasibility and pragmatism. The N-of-1 trials will be iteratively refined in real-time based on this feedback.
Primary Outcome
Qualitative interviews were conducted to assess the feasibility and acceptability of deprescribing N-of-1 trials and participant experiences. Directed content analysis methods were used to develop relevant categories and themes from interview transcript data. Transcripts were coded and analyzed by two team members, consulting additional members to establish consensus where needed. Inter-rater reliability between coders was established.
Interventions
- DRUG Beta blockers
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 9 participants |
| Start Date | 2021-04-01 |
| Est. Completion | 2023-04-28 |
| Phase | Phase 4 |
What the finished NCT04757584 record still lists
NCT04757584 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 9 participants, a relatively small participant target, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (98% lower).
The record links to 0 conditions, and to 1 intervention - of which Beta blockers is the first listed.
NCT04757584 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04757584 about?
NCT04757584 is a clinical study titled "Pilot Deprescribing N-of-1 Trials for Beta-blockers in HFpEF". In this study, we will test the feasibility of N-of-1 trials for deprescribing beta-blockers in patients with Heart Failure with Preserved Ejection Fraction. To achieve this objective we will conduct 16 4-period N-of-1 trials (on vs. off) and subsequently interview participants to better understand ...
What is the current status of trial NCT04757584?
This trial is currently completed. It is a Phase 4 study. The enrollment target is 9 participants. The study started on 2021-04-01. Estimated completion is 2023-04-28.
What interventions are being tested in trial NCT04757584?
The interventions under investigation include: Beta blockers (DRUG).
Who is sponsoring clinical trial NCT04757584?
This trial is sponsored by Weill Medical College of Cornell University, which has 701 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04757584's enrollment target sits among peer trials
9 1968th of 2000 higher than 29 of 2,000 other Phase 4 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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