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NCT04749615 · ClinicalTrials.gov registry record · Phase 4
Does PAI Reduce Pain After TKA Among Knee Arthroplasty Patients Receiving ACB & IPACK?
A Phase 4 study, sponsored by Hospital for Special Surgery, New York.
- Completed
- Registry status
- Phase 4
- Development phase
- 94
- Enrollment target
NCT04749615: Completed Phase 4 study, sponsored by Hospital for Special Surgery, New York.
NCT04749615 is a Phase 4 study that has completed, run by Hospital for Special Surgery, New York. The registered enrollment target is 94 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (82% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04749615, a Phase 4 study, has completed, sponsored by Hospital for Special Surgery, New York.
- COMPLETED
- Registry status
- Phase 4
- Development phase
- 94 participants
- Enrollment target
Study Summary
The goal of this clinical trial is to determine whether Periarticular Injection (PAI) alongside Adductor Canal Block (ACB) and Infiltration between the Popliteal Artery and Capsule of the Knee (IPACK) block can decrease post-operative pain in patients undergoing primary total knee arthroplasty. The main question it aims to answer is: • Is ACB/IPACK without PAI as effective as ACB/IPACK with PAI for TKA patients? Participants will be assigned to one of the following groups at random: * ACB/PACK with PAI * ACB/IPACK with saline injection Participants will also be asked to complete pre- and post-operative questionnaires.
Primary Outcome
The NRS (numeric rating scale) is a questionnaire that measures pain on a numeric scale, 0 (no pain) to 10 (worst pain imaginable). The questionnaire will be asked on post operative discharge day 1.
Interventions
- DRUG Periarticular Injection (PAI)
- DRUG Saline Control Periarticular Injection (PAI)
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 94 participants |
| Start Date | 2020-12-17 |
| Est. Completion | 2022-07-01 |
| Phase | Phase 4 |
What the finished NCT04749615 record still lists
NCT04749615 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 94 participants, a relatively small participant target, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (82% lower).
The record links to 0 conditions, and to 2 interventions - of which Periarticular Injection (PAI) is the first listed.
NCT04749615 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04749615 about?
NCT04749615 is a clinical study titled "Does PAI Reduce Pain After TKA Among Knee Arthroplasty Patients Receiving ACB & IPACK?". The goal of this clinical trial is to determine whether Periarticular Injection (PAI) alongside Adductor Canal Block (ACB) and Infiltration between the Popliteal Artery and Capsule of the Knee (IPACK) block can decrease post-operative pain in patients undergoing primary total knee arthroplasty. The ...
What is the current status of trial NCT04749615?
This trial is currently completed. It is a Phase 4 study. The enrollment target is 94 participants. The study started on 2020-12-17. Estimated completion is 2022-07-01.
What interventions are being tested in trial NCT04749615?
The interventions under investigation include: Periarticular Injection (PAI) (DRUG), Saline Control Periarticular Injection (PAI) (DRUG).
Who is sponsoring clinical trial NCT04749615?
This trial is sponsored by Hospital for Special Surgery, New York, which has 194 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04749615's enrollment target sits among peer trials
94 871st of 2000 higher than 1,127 of 2,000 other Phase 4 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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