Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT04748445 · ClinicalTrials.gov registry record
Acute Respiratory Illness Surveillance (AcRIS) With Mobile Application in a Low-Interventional Decentralized Study.
A clinical trial, sponsored by Pfizer.
- Completed
- Registry status
- 9,151
- Enrollment target
NCT04748445: Completed study, sponsored by Pfizer.
NCT04748445 is a clinical trial that has completed, run by Pfizer. The registered enrollment target is 9,151 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04748445 has completed, sponsored by Pfizer.
- COMPLETED
- Registry status
- 9,151 participants
- Enrollment target
Study Summary
The purpose of the AcRIS study is to obtain data to characterize the relationship between symptoms and voice features for (reverse transcription polymerase chain reaction (RT-PCR) confirmed severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), influenza virus, or Respiratory Syncytial Virus (RSV) positive participants with acute viral respiratory illness. This data will be used as the basis to build voice and symptom algorithm(s) for detection and monitoring of these illnesses. This would benefit vaccine development across several key disease areas, including SARS-CoV-2, influenza virus and RSV. The study also models concepts of more efficient "flexible" clinical trials involving not only voice capture, but also web-based participant recruitment, enhanced participant engagement, and remote sample collection that could make future clinical studies more efficient. The clinical data obtained in this observational study could provide the documentation of the technology's performance needed to enable its deployment in future interventional studies.
Primary Outcome
Symptoms (fever, cough, difficult breathing, fatigue, runny nose, stuffy/blocked nose, sore throat, loss of taste/smell, chills, muscle pain, diarrhea, vomiting, headache, nausea, rigors, wheezing) recorded at least once daily in e-diary for 8 weeks \& rated 0:none to 4:severe for fever \& 0:none to 7:severe for other symptoms. Total symptom score=sum of all symptom scores in a recording session \& mean of daily total symptom score=average across available sessions for each day, range=0 to 109,
Interventions
- DIAGNOSTIC_TEST SARS-CoV-2/Influenza/RSV RT-PCR
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 9,151 participants |
| Start Date | 2021-04-12 |
| Est. Completion | 2022-04-22 |
What the finished NCT04748445 record still lists
NCT04748445 is an observational study that tracks outcomes without assigning an intervention. Its 9,151 participants enrollment target places it among the larger protocols in the corpus.
The record links to 0 conditions, and to 1 intervention - of which SARS-CoV-2/Influenza/RSV RT-PCR is the first listed.
NCT04748445 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04748445 about?
NCT04748445 is a clinical study titled "Acute Respiratory Illness Surveillance (AcRIS) With Mobile Application in a Low-Interventional Decentralized Study.". The purpose of the AcRIS study is to obtain data to characterize the relationship between symptoms and voice features for (reverse transcription polymerase chain reaction (RT-PCR) confirmed severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), influenza virus, or Respiratory Syncytial Virus ...
What is the current status of trial NCT04748445?
This trial is currently completed. The enrollment target is 9,151 participants. The study started on 2021-04-12. Estimated completion is 2022-04-22.
What interventions are being tested in trial NCT04748445?
The interventions under investigation include: SARS-CoV-2/Influenza/RSV RT-PCR (DIAGNOSTIC_TEST).
Who is sponsoring clinical trial NCT04748445?
This trial is sponsored by Pfizer, which has 1,845 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT06946355 · 9,119 participants · NA
Food-based Support for Hospitalized Children and Their Families
- NCT02000089 · 9,000 participants · Phase 3
The Cancer of the Pancreas Screening-5 CAPS5)Study
- NCT05612347 · 8,946 participants · NA
Colonoscopy vs Stool Testing for Older Adults With Colon Polyps
- NCT06284408 · 9,460 participants · NA
Centralized Screening Unit (CSU) at Montefiore-Einstein
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI